ID A0A1M6XDI4_9FLAO Unreviewed; 4658 AA.
AC A0A1M6XDI4;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Amino acid adenylation domain-containing protein {ECO:0000313|EMBL:SHL03865.1};
GN ORFNames=SAMN05444484_10191 {ECO:0000313|EMBL:SHL03865.1};
OS Flavobacterium chilense.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=946677 {ECO:0000313|EMBL:SHL03865.1, ECO:0000313|Proteomes:UP000184028};
RN [1] {ECO:0000313|EMBL:SHL03865.1, ECO:0000313|Proteomes:UP000184028}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24724 {ECO:0000313|EMBL:SHL03865.1,
RC ECO:0000313|Proteomes:UP000184028};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FRBT01000001; SHL03865.1; -; Genomic_DNA.
DR RefSeq; WP_068843419.1; NZ_LSYT01000006.1.
DR STRING; 946677.SAMN05444484_10191; -.
DR OrthoDB; 4317020at2; -.
DR Proteomes; UP000184028; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd05930; A_NRPS; 4.
DR CDD; cd19531; LCL_NRPS-like; 5.
DR Gene3D; 3.30.300.30; -; 4.
DR Gene3D; 3.40.50.980; -; 6.
DR Gene3D; 1.10.1200.10; ACP-like; 4.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 5.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 1.10.10.1830; Non-ribosomal peptide synthase, adenylation domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 5.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR041464; TubC_N.
DR InterPro; IPR044894; TubC_N_sf.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 4.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 4.
DR Pfam; PF00668; Condensation; 5.
DR Pfam; PF00550; PP-binding; 4.
DR Pfam; PF18563; TubC_N; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 4.
DR SUPFAM; SSF47336; ACP-like; 4.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 10.
DR PROSITE; PS00455; AMP_BINDING; 4.
DR PROSITE; PS50075; CARRIER; 4.
PE 4: Predicted;
FT DOMAIN 1015..1090
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2047..2122
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3078..3153
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 4112..4187
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 4658 AA; 530417 MW; BC0D7D067BA1F180 CRC64;
MQALLKKLNN SNIKIDLVDE KLDIQAPKGV MTADLLNEIK LYKNDLIEFI SSYKAKKDKH
QFIPQVPIQH SYVLSSSQHR LWLLSQLESA SVAYNMPSVF QLKGNLDISS LKNAFQLLIE
RHESLRTLFK EEYGEVRQII VPIEDIRFQL EYEDISHNAN LPVKEKEIIK KEIEYSFDLS
QDSLLHAKLI KTTQDTYTFV CVMHHIISDG WSNEVMIREL FTLYNSALNE DPLSPLHIQY
KDYAAWQQNQ LNEADMEKHK AYWLSQFENE LPNLNLPTYQ IRPAIKTYNG KSEKKLFSDI
LVKDFNALCQ SQGSTLFMGL LAIVKVLFYK YTNQKDISIG SPIAGREYLD LQNQIGFYAN
TLALRTCFKE KDNFSDLLAN VKEVTLNAYK HQAYPFDELV EQLPLKRDMS RNPLFDVMIT
LQNTDNLKSG IYRLGEIEVQ NYYLEEDTIS KFDLKFSFIE LDKGLDLIIT YNTDLYTQGF
IERLLGHLET LLQQVTEQPE RAINSLDYLS TDEKQQLLFD FNNTTVTYSE DKTLIDLFEE
QAEKTPDSIA VIFEDKEFTY KEINELSNQL ADYLKANYSI STDDLIGIKL ERSELLIVSI
LGVLKSGAAY VPIDAAYPQE RINYIEKDSN CKIVIDSDEF ENFIGIRSLY KNINPVKTIK
SSDLVYVIYT SGSTGNPKGV MIENTSLVNY LLHQINFLEI KPNERIALLA SVSFDASVEQ
IFTALLSSSA LCIIKKEDVL DAEKLEKIIE KYAITHLHSV PSLLLNLDLS SASSLKRIIS
AGENFKPELA AKYIDKYNLY NKYGPTETTI SSTIGQIVNK DEISIGKPIS NTHIYILNDD
LVPVSLGIIG DMYISGSGLS RGYFNNAAQT ESSFVSNPFQ EGSKMYKTGD LGKWLPDGSI
VFEGRKDFQV KIRGHRIELG EIENVILGYT TSFNQVVVDV REKNSEKVLV AYYSTDGIID
KSELRSYLQS KLPDYMVPGY YLELDSMPLT PNGKIDRKSL PGISGEDLIR REYVAPKTNT
EVKLVKIWEE VLNVEKVGIT DNFFELGGHS LIIVQIINKT FKELGKSISF KDFFANPTIK
GLSKIMYESN YVAIPLAPRS DSYIVTSSQN RLWLLSQLEG GSLAYNMPVA IKLNGILNDE
VFQNAFRYLI NKHEILRTYF KINEGGSLRQ FILSEKEVNF KIDFFDYEGK QPQDIEDLII
SLNNKEFNLE EAPLVRASLL KISDTEHIFF FSRHHIIGDG WSSQIMTSEI IKIYNTLIEG
KEIHSSALKI QYKDYAVWLK NEYNLASIKK SEDYWLEQFS GEIPVLELPG FKTRPLVKTN
NGTQLSYTYS EDFLNKLKNF SKQQNVTLFM TLMAGINTLL YRYSGQKDII IGTPLAGREH
PDLENQIGLY LNTLAIRTQF KEENSFLDLI AVQKETLLEA YQYQNYPFDS LVDKLSLKRD
TSRSVLFDVM VVLQNQNQLK SLNNNEFLNG LEIEEYSFER RTAQFDISFQ FVESERLSLS
IEYNTDIYDA FLINRIFKHF EQLLEQAITA PLLELRHIDY LSSNEKYQVV FDFNDTAAFY
PKDKTILDLF EEQVVMTPNN IAIVFDGKKL IYEDLNEETN QLAEYLKENY AISHKDIVGI
RLDRSASLII SILGVLKAGA AYVPIDPTYP QDRIDYIEKD SASKVIIDEA LFEEFKLVQY
KYSKSNVKKI NSPTDLAYVI YTSGTTGHPK GVQVEHHNLI NLCYWHRTAF KVTGDSRGAL
FSGVGFDASV WEIFPYLISG ASLYPIGEDE IRLNLQKLAD FYNTNEISHT YLPSAICSDL
TNSGLVIEKV KFLVGGEALK IDKGSVLEIY NNYGPTENTV VSSFYKVNQD HKGIIPIGKP
ISNTQIYILD DQLQILPVGV TGKIYVSGAS VARGYLNNEA LTAEKFITNP FEEGKRMYDT
GDLGRWLVDG NIEFLGRKDH QVKIRGYRIE LGEIENTILE FSKTLKQVIV EAKELKSEKV
LVAYIVTEKV LDKTALRNFL QGKLPDYMVP GFYIQLPEFP LTSNGKIDRK KLPEIASEDS
VRKAYVAPGT LIEKELVSIW QNVLGLENIG ITDNFFELGG HSLIISQVIN RVQKQLGSSV
SYKDFFANAT ISGLSKILNT RTYASIAKAP ESEFYPLTGS QNRLWILSQL EGGSLAYNMP
GALRLKGDVD VAKFQTSFEL LIERHEILRT SFKTTPLGEV NQYIIPASVV NFKIIEKDLS
LITNQQEFLV DYLAQSNNEP FDLEHAPLLR ASIIKLKEKE SLFFLTLHHI IGDGWSMEIL
ISEVIKIYNA LLEEKAVELP QLEIQYKDYA VWRNEEQKKE EATENYWLKQ FSGTLPILEL
PGSNARPLVQ TYNGANITRR FSKEFSSKLQ SFSKQQDVTL FMTLMSGINA LLYRYTGQDD
IIIGTPIAGR EHPDLENQIG LYLNTLAIRT RLKEAISFHD LLAIQKETLL KAYEHQNYSF
DSLVGKLNLK RDMSRSALFD VLMVLQSQGQ LNNLNNGTLL NLEVSPYVIE GSNSKFDITY
TFTETDVLSL SINYNTDIYN GDAIERMFAH FENLVIESIN QPLQALETIN YLTEAEKQQL
LVDFNDTKVL HSQDQTLVDL FEEQAAKTPD NTAIIFEDTI LTYQQLNEKA NQLAAYLRAN
YSIEPDDLIA IKLERNEFLL VSLLGVLKSG AAYVPIDSNY PQQRIDYIEK DSNSKVVIDQ
NLVEKFLEVQ HNYSTSNLDQ ISKPNHLAYI IYTSGTTGNP KGVMVEHHNA VELIHWSIKE
FNADKFDIVY AVTSHCFDLS VYEFFYTLST GKQIRMLKNA LEINHYLEQD TNILLNTVPS
VVRKLIEDKV SLDNIKVLNM AGEILPTDII AKLPLDKIEV RNLYGPSEDT TYSTSFFITN
KEARTISIGQ PISNTQVLIL DQNNQLVPVG VTGRIFVSGA GVARGYLNKE ELTQEKFVVN
PFLEGERMYD TGDLGYWLSD GNIEFIGRKD HQVKIRGYRI ELGEIESAVL GFSDQVQQAV
LEAKEFNSQT VLVAYYVSET KIDKTDLRSY LQSKLPDYML PGYFLELDKM PLTPNGKIDR
KALPGISGED LIRREYVAPA TAIEIGLAKI WEEVLNIEKV GTTDNFFELG GHSLVVVQVI
NKTFKELGKS ISFKDFFNNP TIQGLSKKVV ESNYLAIPQA PESSSYPLTS SQNRFWILNQ
FEGASLAYNM PVAVKFTGDL DVLKLEEAFK LLIFRHEILR TAFVSTEGEE VRQLITPKEH
VNFKINYNDF SSKNEIKEAV SSYLANENAV AFDLEKGGLV KGSLLKIQEK EHVFFMSMHH
IVSDGWSMEL LIKEIVSVYN SLVNGTEINL PELKIQYKDY AVWLNSDIQK QKYNAAEQYW
INQFSGELPT LELPSFNKRP LVKTFNGNSI THQFSKEFLD QIKTFSKDND ATLFMSLLAG
TKSLLYKYTN QRDIIIGTPI AGREHPDLEN QVGLYLNTLA IRTQIEENAT ILQVLEKEKQ
ALLEAYQYQN YPFDDLVGKL NLKRNNSRSA LFDVIVVLQN QGQLQITNEE ELTGLQVENY
VFESKTAQLD MSFIFTESEE GLSLTIQYNT DIYDAFLIER IFSHFENLVS NSIANPSAVL
DQTDYLIPSE KQQLLFDFNA TEAAYPKDKT IVALFEEQVE KTPDNTAVVF ENKAFTYQEL
NEISNQLAHY LRENYSIQAD DLIGIKLERS ENLIVSILGI LKSGAAYVPI DPSYPQDRID
YIEKDSASKV IIDEQLLEKF RKVQNDYSKL NVEKINSATD LAYVIYTSGT TGHPKGVMVE
HHNLINLCYW HCTAFKVDKD SRGALFSGVG FDASVWEIFP YLISGASLYP IGEEEIRLNL
RKLADFYNAK EISHSYLPSA ICSELTSSGI VIDNVKFLVG GEALKIDKGS QLDIYNNYGP
TENTVVSTFY KVNPDHNGII PIGKPVCNTQ VYILGDQLQV LPIGVSGKIY VSGASVARGY
LNNETLTSEK FIENPFVSGQ RMYDTGDLGR WLTDGNVEFL GRKDHQVKIR GYRIELGEIE
NTILKFSTPL KQVIVEAKEL NSEKVLVAYI VSENTLDKSA LRNFLQDTLP DYMVPGFFVE
LSHFPLTSNG KIDRKALPSI SSEDIVRKEY VVPITVIEKE IVAIWQSVLG LEKIGVTDNF
FELGGHSLKA GLLINEYRKA FNVKIKVNDI FKSTTIKSHV NLLELTDKID QDEIAKIPEG
ESFAVSAIQK RIWIASQFEN GSKAYHMPSC IEVTINPENF RKAILATIER HEILRTVFKE
SIDAEIKQWI LPLEKLRFEV DYKDYRNIED IEKGIKNFID TDNEKRFDLE NGPLLRAALL
QISDTNYVFY YNIHHIIGDG WSMEVLKNDV LAFYKAYENG GKAELEDLKI QHKDYVAWIA
QNNAGKEQEY WLNKFEKEVP QLDLMVSKER PKIKTYNGNI FSGDITGNNF AKLAETVQNT
ETTFYMNLLS LIYILLYKYS YQKDLVIGSP IDGRDHHSLK NQIGCFVNTV PFRVLLQSKE
NYNSLLARVK NTVLEGLEHQ SFPVESVIEA LELQRDLSRS PLFDVSVVMI QNAVSQDHNP
TNEQGYSKLL ESFKSKLDLT FYFKAYENKI SCNIIYNTDL FDADVIEKMF TEFLILTDFD
LSNDSLTIDD YIATANTNET QEQASFFDDI NAAIDDSF
//
