ID A0A1M6XZR9_9PROT Unreviewed; 386 AA.
AC A0A1M6XZR9;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=galactokinase {ECO:0000256|ARBA:ARBA00012315};
DE EC=2.7.1.6 {ECO:0000256|ARBA:ARBA00012315};
DE AltName: Full=Galactose kinase {ECO:0000256|ARBA:ARBA00029590};
GN ORFNames=SAMN05216428_101122 {ECO:0000313|EMBL:SHL11522.1};
OS Nitrosospira sp. Nsp11.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosospira.
OX NCBI_TaxID=1855338 {ECO:0000313|EMBL:SHL11522.1, ECO:0000313|Proteomes:UP000184455};
RN [1] {ECO:0000313|Proteomes:UP000184455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nsp11 {ECO:0000313|Proteomes:UP000184455};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Carbohydrate metabolism; galactose metabolism.
CC {ECO:0000256|ARBA:ARBA00004947}.
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DR EMBL; FRBV01000001; SHL11522.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M6XZR9; -.
DR STRING; 1855338.SAMN05216428_101122; -.
DR Proteomes; UP000184455; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004335; F:galactokinase activity; IEA:InterPro.
DR GO; GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.890; GHMP kinase, C-terminal domain; 1.
DR InterPro; IPR000705; Galactokinase.
DR InterPro; IPR019539; GalKase_N.
DR InterPro; IPR013750; GHMP_kinase_C_dom.
DR InterPro; IPR036554; GHMP_kinase_C_sf.
DR InterPro; IPR006204; GHMP_kinase_N_dom.
DR InterPro; IPR006203; GHMP_knse_ATP-bd_CS.
DR InterPro; IPR006206; Mevalonate/galactokinase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00131; gal_kin; 1.
DR PANTHER; PTHR10457:SF35; GALACTOKINASE; 1.
DR PANTHER; PTHR10457; MEVALONATE KINASE/GALACTOKINASE; 1.
DR Pfam; PF10509; GalKase_gal_bdg; 1.
DR Pfam; PF08544; GHMP_kinases_C; 1.
DR Pfam; PF00288; GHMP_kinases_N; 1.
DR PIRSF; PIRSF000530; Galactokinase; 1.
DR PRINTS; PR00473; GALCTOKINASE.
DR PRINTS; PR00959; MEVGALKINASE.
DR SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00627; GHMP_KINASES_ATP; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Galactose metabolism {ECO:0000256|ARBA:ARBA00023144};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SHL11522.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 28..74
FT /note="Galactokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10509"
FT DOMAIN 126..194
FT /note="GHMP kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00288"
FT DOMAIN 291..360
FT /note="GHMP kinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08544"
SQ SEQUENCE 386 AA; 41535 MW; 351A868009B3C91D CRC64;
MNAFPGRRDA HAFHGMARNT PGSMKGGFEA AFGRPPEVAA QAPGRVNLLG EHTDYNDGYV
LPIAIEQQTS VSMRRNNQDE YVMHSEILGS KVRFKLDALP AEHFATYVYG CLMEARAAGI
AAPALDIHIE SNVPMGVGLS SSAALEVATL RALRALTGQS LDDVRLAQLA QRAEIEYAGV
RCGIMDQMAS SLAGTQCALF LDTRTLERRL VPLPPASAVL VLDSGIARTL AGSGYNRRRT
ECEEAAKRLG VAALRDVSDI SIADILPEPL RRRVRHVVSE NARVLLAASC HDAMEFGILM
NASHASLRDD YEVSVPELDQ LVGLLQAHPH VYGARLTGAG FGGACVALCE PQALHEISET
VLRGYSSAGF TGRVLVPPTE EAWLDR
//
