ID A0A1M6Z827_9ACTN Unreviewed; 422 AA.
AC A0A1M6Z827;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=RNA polymerase sigma-70 factor, ECF subfamily {ECO:0000313|EMBL:SHL26568.1};
GN ORFNames=SAMN05216499_103248 {ECO:0000313|EMBL:SHL26568.1};
OS Actinacidiphila paucisporea.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Actinacidiphila.
OX NCBI_TaxID=310782 {ECO:0000313|EMBL:SHL26568.1, ECO:0000313|Proteomes:UP000184111};
RN [1] {ECO:0000313|EMBL:SHL26568.1, ECO:0000313|Proteomes:UP000184111}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.2025 {ECO:0000313|EMBL:SHL26568.1,
RC ECO:0000313|Proteomes:UP000184111};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Interacts transiently with the RNA polymerase catalytic core
CC formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1
CC omega subunit) to form the RNA polymerase holoenzyme that can initiate
CC transcription. {ECO:0000256|ARBA:ARBA00011344}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC {ECO:0000256|ARBA:ARBA00010641}.
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DR EMBL; FRBI01000003; SHL26568.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M6Z827; -.
DR STRING; 310782.SAMN05216499_103248; -.
DR Proteomes; UP000184111; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR Gene3D; 1.10.1740.10; -; 1.
DR Gene3D; 3.10.450.50; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30173:SF43; ECF RNA POLYMERASE SIGMA FACTOR SIGI-RELATED; 1.
DR PANTHER; PTHR30173; SIGMA 19 FACTOR; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF08281; Sigma70_r4_2; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000184111};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 103..168
FT /note="RNA polymerase sigma-70 region 2"
FT /evidence="ECO:0000259|Pfam:PF04542"
FT DOMAIN 214..265
FT /note="RNA polymerase sigma factor 70 region 4 type 2"
FT /evidence="ECO:0000259|Pfam:PF08281"
SQ SEQUENCE 422 AA; 45512 MW; 39BF8A9AA5CFC5AF CRC64;
MGRPRVRARS VRPGPPGAVR ELSALVIVCC RASCSLDGGF LSPTPTTQRR GMSGTTRVTF
RRGELSYGRG QPAETEGVAT VMSTRPGPGY DRSDAGPDLD AIMSERRHLL GLAYRLLGSL
AEAEDAVQET YTRWYAMSRQ QQDAVESPGA WLTRVASRVC LDLLGSARAR RERYVGEWIP
EPLPEHTQWA TGRPEDATAD PADRVTLDES VNMAFLVVLE SMTPAERVAF ILHDVFRYPF
AEIAGITGRT PGACRQLASS ARRRIRSARA SANPAARQAG IVRDFMQAWQ ARDIDALVGL
LDPDATMIAD SGGLVAAVLH PVEGGPRIAR AHIDIARAAP DLTLAETTVN GQPGLVAQRD
GLTVTVYAFQ TAGPRITRIW AVRNPEKLHS WTSRRPPGTP HATTIAGHGL AGTHRAAAAV
DP
//
