ID A0A1M6ZZJ1_9PROT Unreviewed; 249 AA.
AC A0A1M6ZZJ1;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Heme exporter protein C {ECO:0000256|ARBA:ARBA00016463, ECO:0000256|RuleBase:RU364092};
DE AltName: Full=Cytochrome c-type biogenesis protein {ECO:0000256|RuleBase:RU364092};
GN Name=ccmC {ECO:0000256|RuleBase:RU364092};
GN ORFNames=SAMN05216428_102139 {ECO:0000313|EMBL:SHL35912.1};
OS Nitrosospira sp. Nsp11.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosospira.
OX NCBI_TaxID=1855338 {ECO:0000313|EMBL:SHL35912.1, ECO:0000313|Proteomes:UP000184455};
RN [1] {ECO:0000313|Proteomes:UP000184455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nsp11 {ECO:0000313|Proteomes:UP000184455};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the export of heme to the periplasm for the
CC biogenesis of c-type cytochromes. {ECO:0000256|ARBA:ARBA00002442,
CC ECO:0000256|RuleBase:RU364092}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU364092}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CcmC/CycZ/HelC family.
CC {ECO:0000256|ARBA:ARBA00005840, ECO:0000256|RuleBase:RU364092}.
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DR EMBL; FRBV01000002; SHL35912.1; -; Genomic_DNA.
DR RefSeq; WP_072766799.1; NZ_FRBV01000002.1.
DR AlphaFoldDB; A0A1M6ZZJ1; -.
DR STRING; 1855338.SAMN05216428_102139; -.
DR Proteomes; UP000184455; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR003557; Cyt_c_biogenesis_CcmC.
DR InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR NCBIfam; TIGR01191; ccmC; 1.
DR PANTHER; PTHR30071:SF17; CYTOCHROME C ASSEMBLY PROTEIN-RELATED; 1.
DR PANTHER; PTHR30071; HEME EXPORTER PROTEIN C; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR PRINTS; PR01386; CCMCBIOGNSIS.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU364092};
KW Cell membrane {ECO:0000256|RuleBase:RU364092};
KW Cytochrome c-type biogenesis {ECO:0000256|RuleBase:RU364092};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364092};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364092};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364092}; Transport {ECO:0000256|RuleBase:RU364092}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 88..109
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 161..180
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 200..222
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT DOMAIN 9..184
FT /note="Cytochrome c assembly protein"
FT /evidence="ECO:0000259|Pfam:PF01578"
SQ SEQUENCE 249 AA; 27680 MW; 845DF5E74AD8F658 CRC64;
MAINWFKYSS PASFYFLAGK MIPLFSVAAI VLFAVGLYIG FFVAPTDFQQ GEAYRIIFIH
VPAAWMSMFL YVVMAMWSGI GLAFNTRLSS MVATAIAPTG AMFTFLALWT GALWGKPMWG
AWWVWDARLT SELILLFLYI GFMSLQAAID DPRRADKAGA MIALVGVVNV PIIYFSVKWW
NTLHQGASVS VTQSPKMATT MLTGMLIMSI ACWMYAIAVV LIRTRTIILE RERHTAWVGE
LQEGVGVAS
//
