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Entry: A0A1M7C7E5_9BACT
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ID   A0A1M7C7E5_9BACT        Unreviewed;       226 AA.
AC   A0A1M7C7E5;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   03-JUL-2019, entry version 11.
DE   RecName: Full=Urease {ECO:0000256|SAAS:SAAS00108089};
DE            EC=3.5.1.5 {ECO:0000256|SAAS:SAAS00108089};
GN   ORFNames=SAMN05720765_11935 {ECO:0000313|EMBL:SHL63124.1};
OS   Fibrobacter sp. UWH6.
OC   Bacteria; Fibrobacteres; Fibrobacterales; Fibrobacteraceae;
OC   Fibrobacter.
OX   NCBI_TaxID=1896212 {ECO:0000313|EMBL:SHL63124.1, ECO:0000313|Proteomes:UP000183970};
RN   [1] {ECO:0000313|EMBL:SHL63124.1, ECO:0000313|Proteomes:UP000183970}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UWH6 {ECO:0000313|EMBL:SHL63124.1,
RC   ECO:0000313|Proteomes:UP000183970};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+);
CC         Xref=Rhea:RHEA:20557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16199, ChEBI:CHEBI:16526, ChEBI:CHEBI:28938;
CC         EC=3.5.1.5; Evidence={ECO:0000256|SAAS:SAAS01115730};
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3)
CC       from urea (urease route): step 1/1.
CC       {ECO:0000256|SAAS:SAAS00108095}.
CC   -!- SUBUNIT: Heterotrimer of UreA (gamma), UreB (beta) and UreC
CC       (alpha) subunits. Three heterotrimers associate to form the active
CC       enzyme. {ECO:0000256|SAAS:SAAS00750638}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00750640}.
CC   -!- SIMILARITY: Belongs to the urease gamma subunit family.
CC       {ECO:0000256|SAAS:SAAS00750641}.
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DR   EMBL; FRAX01000019; SHL63124.1; -; Genomic_DNA.
DR   RefSeq; WP_073160180.1; NZ_FRAX01000019.1.
DR   UniPathway; UPA00258; UER00370.
DR   Proteomes; UP000183970; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-EC.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00407; Urease_beta; 1.
DR   CDD; cd00390; Urease_gamma; 1.
DR   Gene3D; 2.10.150.10; -; 1.
DR   Gene3D; 3.30.280.10; -; 1.
DR   HAMAP; MF_01954; Urease_beta; 1.
DR   HAMAP; MF_01955; Urease_beta_gamma; 1.
DR   HAMAP; MF_00739; Urease_gamma; 1.
DR   InterPro; IPR002019; Urease_beta.
DR   InterPro; IPR036461; Urease_betasu_sf.
DR   InterPro; IPR012010; Urease_gamma.
DR   InterPro; IPR008223; Urease_gamma-beta_su.
DR   InterPro; IPR002026; Urease_gamma/gamma-beta_su.
DR   InterPro; IPR036463; Urease_gamma_sf.
DR   Pfam; PF00699; Urease_beta; 1.
DR   Pfam; PF00547; Urease_gamma; 1.
DR   PIRSF; PIRSF001225; Urease_gammabeta; 1.
DR   SUPFAM; SSF51278; SSF51278; 1.
DR   SUPFAM; SSF54111; SSF54111; 1.
DR   TIGRFAMs; TIGR00192; urease_beta; 1.
DR   TIGRFAMs; TIGR00193; urease_gam; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000183970};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00750644};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00108092}.
SQ   SEQUENCE   226 AA;  24611 MW;  11BA2A1166173B3C CRC64;
     MHLTPRETEK LMLHYAGIVA SERLQRGLKL NYPEAIAYIS SKLLELARDG KTVAELMSEG
     RKMLTAEQVM DGVAEMIHEV QLEATFPDGT KLVTVHDPIP ATGKLIPGEV LVEEGFIELN
     AGKRTLTLDV TNTADRPVQV GSHFHFFEVN KKLDFNRMAA YGMRLDVPAG TAVRFEPGET
     KTVNLVEIGG SREGHGLNGL VEGPMDDEFV KTAAFGRAST SGFTGA
//
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