ID A0A1M7CXA0_9PROT Unreviewed; 702 AA.
AC A0A1M7CXA0;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05216428_105112 {ECO:0000313|EMBL:SHL71846.1};
OS Nitrosospira sp. Nsp11.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosospira.
OX NCBI_TaxID=1855338 {ECO:0000313|EMBL:SHL71846.1, ECO:0000313|Proteomes:UP000184455};
RN [1] {ECO:0000313|Proteomes:UP000184455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nsp11 {ECO:0000313|Proteomes:UP000184455};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FRBV01000005; SHL71846.1; -; Genomic_DNA.
DR RefSeq; WP_072767608.1; NZ_FRBV01000005.1.
DR AlphaFoldDB; A0A1M7CXA0; -.
DR STRING; 1855338.SAMN05216428_105112; -.
DR Proteomes; UP000184455; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd17580; REC_2_DhkD-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:SHL71846.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transferase {ECO:0000313|EMBL:SHL71846.1}.
FT DOMAIN 176..246
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 249..301
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 326..544
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 572..690
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 292..319
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 621
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 702 AA; 79411 MW; 431EEF1D480509AA CRC64;
MMEDNDERQP PFRTLQTSDT ILHASEVVEH ELKQVKEALE EKTRQLDHSL SILRATIEST
ADGILVTDEH DNVLRFNERY LEMWQIHPAI IDTGQHLHLL KFCCKHLADP RQFLDKLEEI
YATWPPDSYD LLELADGRVF ERFSKIQHIE ERRVGRIWSF RDITARKHAE EALRESTERL
RFMAEAMPQK IFTARADGAL DYFNQQWKDY TGLAPEQMAG WEWTKLIHSE DMDESLKRWR
HSLNTGEPFQ MECRFQRADG NYRWHLIQTR ARRDARGNIL MWVGSNTDID SIKRADEEKK
QLLENERIAR SEAERANQLK DEFLATLSHE LRTPLNAILG WSQLILQGTM GKEDIQRGLE
TIERNARAQN KLIEDLLEMS SIISGKVRLD VQLLDFADIA EAAVESIAPA AEAKGIRIRK
TIDPAAGWVS GDNNRLQQVI WNLLSNAVKF TPKGGTVEVI VERASSHLHV VVKDSGMGIK
PEFLAYVFDR FRQADSTLTR NHGGLGLGLA IVKQLVGLHG GTVRAESDGE DKGSAFIISL
PLAPISEKKD HRSAASTQIT FEDGHIALPG VKVLVIDDEQ DARELIKEVL TLFQADVITV
ATAAAGLEIL KNQRPDVIVS DIGMPEKDGY QFIREVRSLP ATDGGKTPAI ALSAFAHSED
RTRAITAGYQ MHLSKPVESH ELVAAIKNLT GLMRKPGVRE HR
//
