ID A0A1M7GFZ8_9GAMM Unreviewed; 392 AA.
AC A0A1M7GFZ8;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:SHM14877.1};
GN ORFNames=SAMN05878437_1485 {ECO:0000313|EMBL:SHM14877.1};
OS Halomonas subglaciescola.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=29571 {ECO:0000313|EMBL:SHM14877.1, ECO:0000313|Proteomes:UP000190911};
RN [1] {ECO:0000313|EMBL:SHM14877.1, ECO:0000313|Proteomes:UP000190911}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACAM 12 {ECO:0000313|EMBL:SHM14877.1,
RC ECO:0000313|Proteomes:UP000190911};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; LT670847; SHM14877.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M7GFZ8; -.
DR STRING; 29571.SAMN05878437_1485; -.
DR InParanoid; A0A1M7GFZ8; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000190911; Chromosome i.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000190911};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:SHM14877.1}.
FT DOMAIN 4..261
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 270..391
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 88
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 348
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 378
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 392 AA; 40492 MW; 4A8C05AE2B938BCD CRC64;
MQDVVIVAAK RSAIGTFGGS LADVPASELG AQVIQDLMQS TGVDPGQIDE VLLGQVLTAG
TGQNPARQAA IGGGLPHAVP AMTINKVCGS GLKALHLATQ AIRCGDAEIV LAGGQENMSA
APHLLPHSRH GQRMGNWTAV DSMVQDGLWD AFNDYHMGIT AENIAEQYAI SREAMDAFAA
ASQHKAHEAI ENGRFDSQIT PIAVPGRKGH VTQFESDEGP RQLTAEKLAG LRPAFRKDGR
VTAGNASGIN DGAAVVMLCS AAKARALGLE PLARIAGYAN AGVDPAIMGM GPAPATRRCL
AKAGWSVDEL DLIEANEAFA AQAIAVNQEL GWDTSRINVN GGAIALGHPI GASGCRILVT
LVHEMLARDA HKGLATLCIG GGQGVALAIE RP
//
