ID A0A1M7HLB1_9PROT Unreviewed; 471 AA.
AC A0A1M7HLB1;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Serine protease Do {ECO:0000313|EMBL:SHM29218.1};
GN ORFNames=SAMN05216428_1227 {ECO:0000313|EMBL:SHM29218.1};
OS Nitrosospira sp. Nsp11.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosospira.
OX NCBI_TaxID=1855338 {ECO:0000313|EMBL:SHM29218.1, ECO:0000313|Proteomes:UP000184455};
RN [1] {ECO:0000313|Proteomes:UP000184455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nsp11 {ECO:0000313|Proteomes:UP000184455};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FRBV01000022; SHM29218.1; -; Genomic_DNA.
DR RefSeq; WP_072768911.1; NZ_FRBV01000022.1.
DR AlphaFoldDB; A0A1M7HLB1; -.
DR STRING; 1855338.SAMN05216428_1227; -.
DR Proteomes; UP000184455; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 2.
DR Gene3D; 2.30.42.10; -; 2.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011782; Pept_S1C_Do.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR NCBIfam; TIGR02037; degP_htrA_DO; 1.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:SHM29218.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..471
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039472378"
FT DOMAIN 253..317
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 374..454
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 356..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 106
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 136
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 209
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
SQ SEQUENCE 471 AA; 50329 MW; 1DF9DCAC6EFDB2A4 CRC64;
MIRKFVLITL IGLSTTVFAQ NRELPDFTSL VEKEGAAVVN ISTVQAPSVV SNRDFPGMPN
IPEDDPFFEF FRRHMQPYGA PRDFESKSLG SGFIISSDGY ILTNAHLVES ADEITVKLTD
KREFRAKLIG ADRKTDIALL KIEASGLPKV TQGDPSKMKV GEWVVAIGSP FGFENSVTAG
IVSAKGRSLT QENFVPFIQT DVAINPGNSG GPLFNMNGEV VGINSQIYSR TGGFMGLSFA
IPIDVATNIS NQLIATGKVS RGRIGVLIQE VTKELAESFG LPKPDGALVA SVQKGSPAEK
AGMEARDVIL KFDGKPVTAA GDLPRIVGAT KPGTKVPVLV WRNGATKEMT VTVDETPPDE
KPVGLGGKRG KAPDTSNRIG LSLSELSADQ KKQLEVDNGL LVEDMVPGIA SHAGVRPGDV
ILSINNQDVT TVEQFNQLLN KTGKGRNIAL LVRRGDTATF ITMKLNGNDS K
//
