ID   A0A1M7IBP1_9RHOB        Unreviewed;       374 AA.
AC   A0A1M7IBP1;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:SHM38182.1};
GN   ORFNames=SAMN05444398_11525 {ECO:0000313|EMBL:SHM38182.1};
OS   Roseovarius pacificus.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Roseovarius.
OX   NCBI_TaxID=337701 {ECO:0000313|EMBL:SHM38182.1, ECO:0000313|Proteomes:UP000183974};
RN   [1] {ECO:0000313|EMBL:SHM38182.1, ECO:0000313|Proteomes:UP000183974}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 29589 {ECO:0000313|EMBL:SHM38182.1,
RC   ECO:0000313|Proteomes:UP000183974};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|RuleBase:RU361277}.
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DR   EMBL; FRBR01000015; SHM38182.1; -; Genomic_DNA.
DR   RefSeq; WP_073036880.1; NZ_FRBR01000015.1.
DR   AlphaFoldDB; A0A1M7IBP1; -.
DR   STRING; 337701.SAMN05444398_11525; -.
DR   OrthoDB; 9770544at2; -.
DR   Proteomes; UP000183974; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08281; liver_ADH_like1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43880; ALCOHOL DEHYDROGENASE; 1.
DR   PANTHER; PTHR43880:SF12; ALCOHOL DEHYDROGENASE CLASS-3; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183974};
KW   Zinc {ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          19..371
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   374 AA;  39433 MW;  B13210D31C7CA6BF CRC64;
     MKIQAAVLER ENIERDFEKN KALTVRDVEL DEPGRGEVLI RVAAAGVCHS DLSVINGTRP
     RPVPMVLGHE ASGIVEQVGP GIDDLAPGDH VVCIFAPGCG TCLPCSEGRP ALCTRAAKHH
     GVGELMTGHR RLSMDGKPVH HHVGVSAFAT HAVLARQSLV KVDVDIPTHI SALFSCAMLT
     GAGAVFNTAR VTPGSKVAVV GLGGVGLSAV LGAQAAGAGQ IVVIDPFDSK LETAMDMGAT
     HTVKADEHTT EAVRDLTGGG VDYAIELAGS VKALETAYDC TCRGGTTVTA GLPHPDARMP
     LNALKLVAEE RALKGSYIGS CVPQRDLPRM FSLHQQGKLP VEKMLTHRLR LDQINLAMDQ
     LDDGTAIRQV IEFN
//