ID A0A1M7IKC4_9FLAO Unreviewed; 331 AA.
AC A0A1M7IKC4;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=1-phosphatidylinositol phosphodiesterase {ECO:0000256|ARBA:ARBA00019758};
DE EC=4.6.1.13 {ECO:0000256|ARBA:ARBA00012581};
DE AltName: Full=Phosphatidylinositol diacylglycerol-lyase {ECO:0000256|ARBA:ARBA00030474};
DE AltName: Full=Phosphatidylinositol-specific phospholipase C {ECO:0000256|ARBA:ARBA00030782};
GN ORFNames=SAMN05444407_11517 {ECO:0000313|EMBL:SHM41105.1};
OS Chryseobacterium contaminans.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=1423959 {ECO:0000313|EMBL:SHM41105.1, ECO:0000313|Proteomes:UP000184069};
RN [1] {ECO:0000313|EMBL:SHM41105.1, ECO:0000313|Proteomes:UP000184069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 27621 {ECO:0000313|EMBL:SHM41105.1,
RC ECO:0000313|Proteomes:UP000184069};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = 1D-myo-
CC inositol 1,2-cyclic phosphate + a 1,2-diacyl-sn-glycerol;
CC Xref=Rhea:RHEA:17093, ChEBI:CHEBI:17815, ChEBI:CHEBI:57880,
CC ChEBI:CHEBI:58484; EC=4.6.1.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001316};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FRBM01000015; SHM41105.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M7IKC4; -.
DR STRING; 1423959.SAMN05444407_11517; -.
DR OrthoDB; 7191982at2; -.
DR Proteomes; UP000184069; Unassembled WGS sequence.
DR GO; GO:0004436; F:phosphatidylinositol diacylglycerol-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd08586; PI-PLCc_BcPLC_like; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR InterPro; IPR000909; PLipase_C_PInositol-sp_X_dom.
DR PANTHER; PTHR13593:SF148; SI:DKEY-152B24.6-RELATED; 1.
DR PANTHER; PTHR13593; UNCHARACTERIZED; 1.
DR Pfam; PF00388; PI-PLC-X; 1.
DR SMART; SM00148; PLCXc; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS50007; PIPLC_X_DOMAIN; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..331
FT /note="1-phosphatidylinositol phosphodiesterase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012974909"
FT DOMAIN 64..207
FT /note="Phosphatidylinositol-specific phospholipase C X"
FT /evidence="ECO:0000259|SMART:SM00148"
SQ SEQUENCE 331 AA; 36652 MW; C4CCAA49B622BB5F CRC64;
MFKHMKYVKK FTLCIATATV FFSCSEAVAE RDSNEVSLTS VNKANSKMTA AVPVEMNSWM
AGLQDNISLS KISIPGTHDS GARIDAPVVT GTAKTQDLSI AEQLNAGVRF LDIRCRHIDN
SFTIHHGAIY QNLNFDDVLN ACYAFLENHP SETIIMSVKE EHDASNTTRS FESTFDSYVQ
KNPSKWDLGT NIPTLGEVRG KIRLLRRFSA GTAKGINATS WADNTTFEIN NPDAQIKVQD
YYKVTNNDDK WNSISNLLGE AKNSTSDRLF INFTSGYKPG IFGIPSIPTV SNAINPKLKT
FFQSNTKGSY GIMPIDFVNA ELAELIVKTN F
//
