ID A0A1M7K9R1_9ACTN Unreviewed; 499 AA.
AC A0A1M7K9R1;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=SAMN05216499_112195 {ECO:0000313|EMBL:SHM62039.1};
OS Actinacidiphila paucisporea.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Actinacidiphila.
OX NCBI_TaxID=310782 {ECO:0000313|EMBL:SHM62039.1, ECO:0000313|Proteomes:UP000184111};
RN [1] {ECO:0000313|EMBL:SHM62039.1, ECO:0000313|Proteomes:UP000184111}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.2025 {ECO:0000313|EMBL:SHM62039.1,
RC ECO:0000313|Proteomes:UP000184111};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
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DR EMBL; FRBI01000012; SHM62039.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M7K9R1; -.
DR STRING; 310782.SAMN05216499_112195; -.
DR OrthoDB; 9763537at2; -.
DR Proteomes; UP000184111; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000184111}.
FT DOMAIN 2..127
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 131..463
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 294
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 499 AA; 54058 MW; C4AECE66940867D1 CRC64;
MIIPHPTHLA RIPGHFTFDE STTLRASGDA LGAARLLRTL LAPATGLPLR HSPTGNVVLV
VDSMLGGLGE EGYGLTVGPD AVLLRAARPA GLLRGVQTIR QLLPPQALSA RPVADVPWRI
PGVQMTDVPR FAWRGAMLDV ARHFQPVSFL KRFTDLLAFH KLNVLHLHLT DDQGWRMPVD
AYPALTEVGS VRGGAEPHAG AYTAAELRGL VAYAAERGVA VVPEIEMPGH ARAALAAYPR
LGNVPGRALE VWTQWGVCDT VLGVHDEVLD FCRTVLGEVL DVFPSPYVHV GGDECPVTEW
ETSTAARRRA AELGLGSPKE LHGWFLGQVG DFLLAQGRRP LCWAEDSGAL PADFTVMPWR
DAAHGLAAAR RGHDVIMTPY RSTYLDYPQS DDPAEPPGQA GGVVDLRAVH RNDPAPADWE
PAAAARVLGT QAQLWTEYVR TPGQAEYLAF PRLAALADRA WNPASDWATD FRPALRLHEA
RLDALRVPRR GPAPTTTSH
//
