ID   A0A1M7KQD8_9ACTN        Unreviewed;       345 AA.
AC   A0A1M7KQD8;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Aminodeoxyfutalosine deaminase {ECO:0000313|EMBL:SHM67722.1};
GN   ORFNames=SAMN05216499_11363 {ECO:0000313|EMBL:SHM67722.1};
OS   Actinacidiphila paucisporea.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Actinacidiphila.
OX   NCBI_TaxID=310782 {ECO:0000313|EMBL:SHM67722.1, ECO:0000313|Proteomes:UP000184111};
RN   [1] {ECO:0000313|EMBL:SHM67722.1, ECO:0000313|Proteomes:UP000184111}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.2025 {ECO:0000313|EMBL:SHM67722.1,
RC   ECO:0000313|Proteomes:UP000184111};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
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DR   EMBL; FRBI01000013; SHM67722.1; -; Genomic_DNA.
DR   RefSeq; WP_073500372.1; NZ_FRBI01000013.1.
DR   AlphaFoldDB; A0A1M7KQD8; -.
DR   STRING; 310782.SAMN05216499_11363; -.
DR   OrthoDB; 105475at2; -.
DR   Proteomes; UP000184111; Unassembled WGS sequence.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   CDD; cd01320; ADA; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   NCBIfam; TIGR01430; aden_deam; 1.
DR   PANTHER; PTHR43114; ADENINE DEAMINASE; 1.
DR   PANTHER; PTHR43114:SF6; ADENINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000184111}.
FT   DOMAIN          18..339
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   345 AA;  37152 MW;  59F6DC086EAF82E3 CRC64;
     MPDSAPAGGL DAFIAGLPKA ELHVHHVGSA SPRIVAELAA RHPDSAVPAD PAALADYFSF
     RDFAHFIDVY LSVVDLIRDA EDVRLLTFEV ARDMARQNVR YAELTVTPYS STRRGIPDRD
     FMAAIEDARK AAEAELGVTL RWCFDIPGEA GLASAEETLR LAVDLRPEGL VSFGLGGPEI
     GVPRPQFKPY FDRARAAGLH SVPHAGETTG PETIWDALRE LGAERIGHGT SAVRDPRLLD
     HLAEHRIPLE VCPTSNIATR AVATLDEHPI RQMVEAGVLV TVNSDDPPMF GTDLNTEYAV
     AARLLELDHL GVAGLAKNAV EASFLDAPGK ARLAAEIDAY AAAWH
//