ID A0A1M7LJZ3_9BACT Unreviewed; 456 AA.
AC A0A1M7LJZ3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Exodeoxyribonuclease 7 large subunit {ECO:0000256|RuleBase:RU004355};
DE EC=3.1.11.6 {ECO:0000256|RuleBase:RU004355};
GN ORFNames=SAMN05444266_11112 {ECO:0000313|EMBL:SHM78442.1};
OS Chitinophaga jiangningensis.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Chitinophaga.
OX NCBI_TaxID=1419482 {ECO:0000313|EMBL:SHM78442.1, ECO:0000313|Proteomes:UP000184420};
RN [1] {ECO:0000313|EMBL:SHM78442.1, ECO:0000313|Proteomes:UP000184420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 27406 {ECO:0000313|EMBL:SHM78442.1,
RC ECO:0000313|Proteomes:UP000184420};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-
CC direction to yield nucleoside 5'-phosphates.; EC=3.1.11.6;
CC Evidence={ECO:0000256|RuleBase:RU004355};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU004355}.
CC -!- SIMILARITY: Belongs to the XseA family.
CC {ECO:0000256|RuleBase:RU004355}.
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DR EMBL; FRBL01000011; SHM78442.1; -; Genomic_DNA.
DR RefSeq; WP_073086558.1; NZ_FRBL01000011.1.
DR AlphaFoldDB; A0A1M7LJZ3; -.
DR STRING; 1419482.SAMN05444266_11112; -.
DR OrthoDB; 9802795at2; -.
DR Proteomes; UP000184420; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:UniProtKB-EC.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006308; P:DNA catabolic process; IEA:InterPro.
DR InterPro; IPR003753; Exonuc_VII_L.
DR InterPro; IPR020579; Exonuc_VII_lsu_C.
DR InterPro; IPR025824; OB-fold_nuc-bd_dom.
DR NCBIfam; TIGR00237; xseA; 1.
DR PANTHER; PTHR30008; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR PANTHER; PTHR30008:SF0; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR Pfam; PF02601; Exonuc_VII_L; 1.
DR Pfam; PF13742; tRNA_anti_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000256|RuleBase:RU004355};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU004355};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|RuleBase:RU004355};
KW Reference proteome {ECO:0000313|Proteomes:UP000184420}.
FT DOMAIN 8..114
FT /note="OB-fold nucleic acid binding"
FT /evidence="ECO:0000259|Pfam:PF13742"
FT DOMAIN 150..441
FT /note="Exonuclease VII large subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02601"
SQ SEQUENCE 456 AA; 51150 MW; 00A0695A782BFD34 CRC64;
MSHPNAIRLS ELSARIRAVV QQAFAGQSYW VKADITSHSF YPDKNIHYFD LVEKDERSGI
VARVAANAWG NGSRQIKAFE LITGQPFRNN IHVLVQVTVS YHQVHGLQVT VQDVDISFTI
GQLEQQKQQT LARLLAENAD AVRLVGERYI TRNQELPLPA VIQQIAVVTS GNSAGYQDFH
HTLVNNGFGY TFKLDTYFTV VQGEANAELV QQRMVDVFNA GKAYDVVVII RGGGAQTDFL
LFDSYQLGRV VARFPIPVIT GIGHQKNETV TDMMAHTAVK TPTKAAELII AHNRGYEDAL
LQFRQRILVR AQQAVAMGNR QMYHLQQDII NKTRAILGVG REELLHLRHG IDRGAKQLLQ
QQKQQVLFMQ AALLARPGTR LQREQEKLRQ QQQFFKMLAP ESMLKRGFAL VYKNGELLKD
AADITAGNNI TIQLQDTAIQ AVVQSKSNTD ERGTDI
//
