ID A0A1M7MW11_9ACTN Unreviewed; 506 AA.
AC A0A1M7MW11;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Predicted PurR-regulated permease PerM {ECO:0000313|EMBL:SHM95362.1};
GN ORFNames=SAMN05443668_102300 {ECO:0000313|EMBL:SHM95362.1};
OS Cryptosporangium aurantiacum.
OC Bacteria; Actinomycetota; Actinomycetes; Cryptosporangiales;
OC Cryptosporangiaceae; Cryptosporangium.
OX NCBI_TaxID=134849 {ECO:0000313|EMBL:SHM95362.1, ECO:0000313|Proteomes:UP000184440};
RN [1] {ECO:0000313|EMBL:SHM95362.1, ECO:0000313|Proteomes:UP000184440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 46144 {ECO:0000313|EMBL:SHM95362.1,
RC ECO:0000313|Proteomes:UP000184440};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC family. {ECO:0000256|ARBA:ARBA00009773}.
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DR EMBL; FRCS01000002; SHM95362.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M7MW11; -.
DR STRING; 134849.SAMN05443668_102300; -.
DR OrthoDB; 5242074at2; -.
DR Proteomes; UP000184440; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR002549; AI-2E-like.
DR PANTHER; PTHR21716; TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR21716:SF75; TRANSPORT PROTEIN SLL0063-RELATED; 1.
DR Pfam; PF01594; AI-2E_transport; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000184440};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 96..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 23..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 440..506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..90
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 506 AA; 54832 MW; 670EB354B52F220B CRC64;
MAKRERRLAL PAYARAAWQR VAAGRPGGRH RSAGHPSASE AVTSPPAVEM AAEHERPDPR
RAASVDDLGD PTFGRDDAER HRSPGDRRRS DRMPRWLPRA FLLAMLTVSA FFLAWWLLGR
LRDLIGLLLL AQFLAFALEP AVNWLARRGW RRGAATGVTM LVVLASLIGF MVAVGSLLVS
QVTTLSARFP QYLELTIEWV NSTFDTNISI QQIQNQVTAN DGPLRRWAEG VASNAVDLST
SVFGVIFQTL TVILFGYYLC ADAPRVRRSL CSVLPPARQR DVMRAWEIAV DKTGGYLYSR
LLLALVSSLA HYIVLTLLGV PYAVALALWV GLVSQLIPTV GTYLAAAMPL IVALVSHPVD
ALFLLVFVVI YQQVENYLLQ PKITARTLDL HPAVAFGAVL AGAAVLGPIG AILAIPFTAI
SQTFVGSYIR RYEVEEHPIH EPVAKGPIES PPPMPPRHGD DAPHHADGSL AAPASPEETP
VEELTPEAAP APVSPPRPAG TSSATT
//
