ID   A0A1M7NB60_9SPHI        Unreviewed;       981 AA.
AC   A0A1M7NB60;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE            EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN   ORFNames=SAMN05216524_104536 {ECO:0000313|EMBL:SHN00797.1};
OS   Mucilaginibacter sp. OK098.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Mucilaginibacter.
OX   NCBI_TaxID=1855297 {ECO:0000313|EMBL:SHN00797.1, ECO:0000313|Proteomes:UP000184158};
RN   [1] {ECO:0000313|EMBL:SHN00797.1, ECO:0000313|Proteomes:UP000184158}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OK098 {ECO:0000313|EMBL:SHN00797.1,
RC   ECO:0000313|Proteomes:UP000184158};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC         Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC         ChEBI:CHEBI:173112; EC=2.7.7.7;
CC         Evidence={ECO:0000256|ARBA:ARBA00024632};
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DR   EMBL; FRCM01000004; SHN00797.1; -; Genomic_DNA.
DR   RefSeq; WP_073404810.1; NZ_FRCM01000004.1.
DR   AlphaFoldDB; A0A1M7NB60; -.
DR   STRING; 1855297.SAMN05216524_104536; -.
DR   OrthoDB; 9803237at2; -.
DR   Proteomes; UP000184158; Unassembled WGS sequence.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd07431; PHP_PolIIIA; 1.
DR   Gene3D; 1.10.150.870; -; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR011708; DNA_pol3_alpha_NTPase_dom.
DR   InterPro; IPR040982; DNA_pol3_finger.
DR   InterPro; IPR004805; DnaE2/DnaE/PolC.
DR   InterPro; IPR029460; DNAPol_HHH.
DR   InterPro; IPR004013; PHP_dom.
DR   InterPro; IPR003141; Pol/His_phosphatase_N.
DR   InterPro; IPR016195; Pol/histidinol_Pase-like.
DR   PANTHER; PTHR32294; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR   Pfam; PF07733; DNA_pol3_alpha; 1.
DR   Pfam; PF17657; DNA_pol3_finger; 1.
DR   Pfam; PF14579; HHH_6; 1.
DR   Pfam; PF02811; PHP; 1.
DR   SMART; SM00481; POLIIIAc; 1.
DR   SUPFAM; SSF89550; PHP domain-like; 1.
PE   4: Predicted;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          1..68
FT                   /note="Polymerase/histidinol phosphatase N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00481"
SQ   SEQUENCE   981 AA;  112179 MW;  04888584D8BF1A1B CRC64;
     MYLNTHSQFS LRYGTMDIKA IVKGAKACGI EQLALTDINN SSGIMEFVRL AEKEGVKPIA
     GMEFHRDKQL LYIGIARNRE GFKELNDFLT FHNVNHQPLP DQPWDFQNAY VIYPFTGDTD
     LALKENEYIG IRYEQLNSLF GRPLAKIKDK LVALCPVTVS DKIEYRLHEY LRAIDLSTLL
     TKVGESYKCR PNEMFLPPDD LRRQFSMYPF IISNTEKVMM ACDIKVPDEK SRNKKTFTGS
     MQGDYDRLRE LTMEGMLYRF GTGHEKALKK IEEELLVIRD QGFAPYFLIT HDITTHFMKK
     GYYHVGRGSG ANSTVAYCLR ITDVDPMELD LYFERFLNKS RTSPPDFDID YSWDQRVEVQ
     QYIFDKYTYQ HVALLGTMST FKDRSVIREI GKVMGLPPAE IDSFTDRSIN DQRENNPAFK
     KIMAVHDRMK NMPNQRSIHA GGVLISEEPI TYFTALDMPP KGMQTVQWDM YEAEAIGFEK
     FDILSQRGIG HIKEAAQLIE DNKGEKVDIH DFRRFKSDGV INTQLKTSDS IGCFYIESPA
     MRQLLRKLQC GDYLTLVAAS SIIRPGVAQS GMMQAYIRNF HNPENVVYLH PVMKEQLEET
     YGVMVYQEDV IKVCIHFAGM DGSDADILRR GMSGKYRSKI EFDKLVDKFF IGAKALGRSD
     DITAEVWRQV SSFAGYSFSK AHSASFAVES YQSLFLKTYY PMEFMVAVLN NYGGFYSRWL
     YVHELQKAGA RVQLPCVNHS ETTVGIKGVD AFLGLIGISG LENRFIESIP EERHMNGPFC
     GLEDFIKRTS ITLEQCITLI RVGALRFTGS SKKELLWEVH NYLGSKPPPK PVNELFNIPA
     KACQLPELVN TALEDAYNEL ELLGYPVTLT MFDLLRSSFR GDVMTKDLVA HTGKIVRMVG
     NYVCEKTVHT KNNKLMWFGT FLDAQGDFFD TTHFPDATPG YPFKGKGCYL IEGKVVQDFG
     FPSVEVLKFF KLRIKDNPVY Y
//