ID A0A1M7PSC3_9ACTN Unreviewed; 372 AA.
AC A0A1M7PSC3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Signal transduction histidine kinase {ECO:0000313|EMBL:SHN20260.1};
GN ORFNames=SAMN05443668_103633 {ECO:0000313|EMBL:SHN20260.1};
OS Cryptosporangium aurantiacum.
OC Bacteria; Actinomycetota; Actinomycetes; Cryptosporangiales;
OC Cryptosporangiaceae; Cryptosporangium.
OX NCBI_TaxID=134849 {ECO:0000313|EMBL:SHN20260.1, ECO:0000313|Proteomes:UP000184440};
RN [1] {ECO:0000313|EMBL:SHN20260.1, ECO:0000313|Proteomes:UP000184440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 46144 {ECO:0000313|EMBL:SHN20260.1,
RC ECO:0000313|Proteomes:UP000184440};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FRCS01000003; SHN20260.1; -; Genomic_DNA.
DR RefSeq; WP_073256847.1; NZ_FRCS01000003.1.
DR AlphaFoldDB; A0A1M7PSC3; -.
DR STRING; 134849.SAMN05443668_103633; -.
DR OrthoDB; 227596at2; -.
DR Proteomes; UP000184440; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SHN20260.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000184440};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 47..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 174..239
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT DOMAIN 284..369
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
SQ SEQUENCE 372 AA; 39408 MW; 9EB07FE5FE4E3A3A CRC64;
MNRLLRLLWD EPPPPQPPAP VRRDRALLAV LALFVLLEGL LRPDLPGRAV TIVVGLGLLP
TLLWRRSRPL LAVVVAFGVT GVAAPVIGAE PRLASMIYLL LLPYGLFRWG SGREIVIGSG
VLLAKVGTGL LVDLTPGDAA GGLAVLVATA ATGTAIRYRA NARARELDQV KLVERERLAR
DLHDTVAHHV SAMAIRAQAG IAVAETEPGA AVDALRVIEA EASRTLAEMR SIVRVLRSDE
AVERLPAPRA ADLARLAGDT AGGPHVDVRL VGDLEHLPPP IDSAIYRLGQ ESVTNARRHA
RHATRIDVRV VADGDTVQLR VSDDGEPGSP HAPGYGILGM IERADLLGGH CAAGPAPDRG
WTVDVVLPRA AT
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