ID   A0A1M7Q3K0_9ACTN        Unreviewed;       445 AA.
AC   A0A1M7Q3K0;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Ribonuclease HI {ECO:0000313|EMBL:SHN24764.1};
GN   ORFNames=SAMN05443668_10491 {ECO:0000313|EMBL:SHN24764.1};
OS   Cryptosporangium aurantiacum.
OC   Bacteria; Actinomycetota; Actinomycetes; Cryptosporangiales;
OC   Cryptosporangiaceae; Cryptosporangium.
OX   NCBI_TaxID=134849 {ECO:0000313|EMBL:SHN24764.1, ECO:0000313|Proteomes:UP000184440};
RN   [1] {ECO:0000313|EMBL:SHN24764.1, ECO:0000313|Proteomes:UP000184440}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 46144 {ECO:0000313|EMBL:SHN24764.1,
RC   ECO:0000313|Proteomes:UP000184440};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FRCS01000004; SHN24764.1; -; Genomic_DNA.
DR   RefSeq; WP_073257521.1; NZ_FRCS01000004.1.
DR   AlphaFoldDB; A0A1M7Q3K0; -.
DR   STRING; 134849.SAMN05443668_10491; -.
DR   Proteomes; UP000184440; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF00075; RNase_H; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50879; RNASE_H_1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000184440}.
FT   DOMAIN          9..141
FT                   /note="RNase H type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS50879"
FT   REGION          185..355
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        205..224
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        263..277
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   445 AA;  45758 MW;  78E55AEC9EF8DEB0 CRC64;
     MVEQAAPADD RRVVIYASGS GGASPGAGGW GALLTHGESR RELSGAETGA TRDRMSLLAV
     VSAVECLTRP TTVLVLTDNE YVRAGVAARL QGGDTDPQDT DLWTRLGAAV TRHRVQWVVV
     DAALATRATT LAAAAASPAG RASPADRAAL ADRAALAGRA SPADRAALAD RAALADRAAL
     ADRAAARPGR AAGPASPARP ERAPAQRENA SRRPDADRPA APAREPEPAV KPRPVADAAP
     AAKPAPAAGP TPVADAAPAA RPGPAGEPVP VQVPTAPGPT ASAPAGRALP REVVAAMRPA
     STLQRPSGER ASLPFRPGDA PPVPRTDGAP DTGVADPGAA DPAADPDPDD IDELRDEFVD
     ELRFWLEDET DLADSAVDEW LRETLLRIVD VTEESITFDD PTGRTIGPVP VPAGIAEQAE
     PGWRVRLTAA RTGDTWRLRG GEPSP
//