ID A0A1M7QC56_9BACI Unreviewed; 507 AA.
AC A0A1M7QC56;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Exopolyphosphatase {ECO:0000256|ARBA:ARBA00020416};
DE EC=3.6.1.11 {ECO:0000256|ARBA:ARBA00012451};
GN ORFNames=SAMN05216179_3047 {ECO:0000313|EMBL:SHN28329.1};
OS Gracilibacillus kekensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Gracilibacillus.
OX NCBI_TaxID=1027249 {ECO:0000313|EMBL:SHN28329.1, ECO:0000313|Proteomes:UP000184184};
RN [1] {ECO:0000313|EMBL:SHN28329.1, ECO:0000313|Proteomes:UP000184184}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.10681 {ECO:0000313|EMBL:SHN28329.1,
RC ECO:0000313|Proteomes:UP000184184};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[phosphate](n) + H2O = [phosphate](n-1) + H(+) + phosphate;
CC Xref=Rhea:RHEA:21528, Rhea:RHEA-COMP:9859, Rhea:RHEA-COMP:14279,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16838,
CC ChEBI:CHEBI:43474; EC=3.6.1.11;
CC Evidence={ECO:0000256|ARBA:ARBA00000209};
CC -!- SIMILARITY: Belongs to the GppA/Ppx family.
CC {ECO:0000256|ARBA:ARBA00007125}.
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DR EMBL; FRCZ01000006; SHN28329.1; -; Genomic_DNA.
DR RefSeq; WP_073202693.1; NZ_FRCZ01000006.1.
DR AlphaFoldDB; A0A1M7QC56; -.
DR STRING; 1027249.SAMN05216179_3047; -.
DR OrthoDB; 9807195at2; -.
DR Proteomes; UP000184184; Unassembled WGS sequence.
DR GO; GO:0004309; F:exopolyphosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0006793; P:phosphorus metabolic process; IEA:InterPro.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR022371; Exopolyphosphatase.
DR InterPro; IPR048950; Ppx_GppA_C.
DR InterPro; IPR003695; Ppx_GppA_N.
DR InterPro; IPR030673; PyroPPase_GppA_Ppx.
DR NCBIfam; TIGR03706; exo_poly_only; 1.
DR PANTHER; PTHR30005; EXOPOLYPHOSPHATASE; 1.
DR PANTHER; PTHR30005:SF0; RETROGRADE REGULATION PROTEIN 2; 1.
DR Pfam; PF02541; Ppx-GppA; 1.
DR Pfam; PF21447; Ppx-GppA_III; 1.
DR PIRSF; PIRSF001267; Pyrophosphatase_GppA_Ppx; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000184184}.
FT DOMAIN 24..304
FT /note="Ppx/GppA phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02541"
FT DOMAIN 316..476
FT /note="Ppx/GppA phosphatase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21447"
SQ SEQUENCE 507 AA; 58557 MW; 5E96057723299610 CRC64;
MKKQYYAIID IGSNTMRLVI YLREQGGRLK EVENVKAVAR LRTFLDEDNH LNKAGIERLV
TTLKSFQDVL EIYPLQEVVC VATATIRQAT NKEEIVIQAE KETGMTMRIL SDQEEAYYGY
LAVVNSTSIS TGITVDIGGG STEVTYFKDR ELQHAHSFPF GALTLKEFFT KEIPTDDELQ
KLRIYLTKHF KTLPWLSDKE VPLIAIGGSA RNLVQIDQNL KEYPLAGLHQ YKMYDTDIKN
VSNYLTSLKP EKLSKVEGLS KDRADIIIPA IEVFHSLYQI TQADSFILSR KGLRDGVFYE
QLSKETGSIL FPNVLEDSIQ ELINDYNLEP KQILHVQYLT RKLFDCLKEN GLIHLDKKDW
NLLKRASYLC NLGEYIDAES SAQHTFYLLA NRTIDGLMHK DRLRLALIAS YKNKTVFKQF
IKPYKSWFLK DERKRLRHLG ALLKFSYCLD ATKRQVIKDI TCSHKNNKLY LTLHCEGDAT
PEEYQSEKQK KHVEKAIKKE IELDFKL
//
