ID   A0A1M7R6F7_9ACTN        Unreviewed;       331 AA.
AC   A0A1M7R6F7;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Ketopantoate reductase {ECO:0000313|EMBL:SHN41925.1};
GN   ORFNames=SAMN05443668_10822 {ECO:0000313|EMBL:SHN41925.1};
OS   Cryptosporangium aurantiacum.
OC   Bacteria; Actinomycetota; Actinomycetes; Cryptosporangiales;
OC   Cryptosporangiaceae; Cryptosporangium.
OX   NCBI_TaxID=134849 {ECO:0000313|EMBL:SHN41925.1, ECO:0000313|Proteomes:UP000184440};
RN   [1] {ECO:0000313|EMBL:SHN41925.1, ECO:0000313|Proteomes:UP000184440}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 46144 {ECO:0000313|EMBL:SHN41925.1,
RC   ECO:0000313|Proteomes:UP000184440};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FRCS01000008; SHN41925.1; -; Genomic_DNA.
DR   RefSeq; WP_073260293.1; NZ_FRCS01000008.1.
DR   AlphaFoldDB; A0A1M7R6F7; -.
DR   STRING; 134849.SAMN05443668_10822; -.
DR   OrthoDB; 9796561at2; -.
DR   Proteomes; UP000184440; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR013752; KPA_reductase.
DR   InterPro; IPR013332; KPR_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR21708:SF42; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR   PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR   Pfam; PF02558; ApbA; 1.
DR   Pfam; PF08546; ApbA_C; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000184440}.
FT   DOMAIN          4..107
FT                   /note="Ketopantoate reductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02558"
FT   DOMAIN          203..321
FT                   /note="Ketopantoate reductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08546"
SQ   SEQUENCE   331 AA;  34290 MW;  729623B938F95A00 CRC64;
     MRNVCIVGAG AVGGVLGARL AASGVRTAAL ARGATLDALR THGWRLREGA AGEIVTAPAV
     VSDDPAELGV QDLVVLSVKA TALVDAVRAL PPLLGPHTTV LTAMNGVPWW FFAAGAGVPA
     ELRGLRLRAV DPDGSVAAAV PADRVLGGVV HYSASVVEPG FAARNAGREL IIGEPDGSRS
     DRATEVTALL TAAGFATTLS DRIQADVWYK LWGNMTMNPV SVLTGATSDL ILDDPLVHEF
     CVAVMREAAE VGDRIGCHID ETPADRMVVT RKLGAMTTSM LQDARSGRPI ELDALVGAVR
     EIAAAVGVAT PHTDALHGLA RLNGRTRGLY P
//