ID A0A1M7R8L1_9ACTN Unreviewed; 424 AA.
AC A0A1M7R8L1;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Probable phosphoglycerate mutase {ECO:0000313|EMBL:SHN42480.1};
GN ORFNames=SAMN05443668_108223 {ECO:0000313|EMBL:SHN42480.1};
OS Cryptosporangium aurantiacum.
OC Bacteria; Actinomycetota; Actinomycetes; Cryptosporangiales;
OC Cryptosporangiaceae; Cryptosporangium.
OX NCBI_TaxID=134849 {ECO:0000313|EMBL:SHN42480.1, ECO:0000313|Proteomes:UP000184440};
RN [1] {ECO:0000313|EMBL:SHN42480.1, ECO:0000313|Proteomes:UP000184440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 46144 {ECO:0000313|EMBL:SHN42480.1,
RC ECO:0000313|Proteomes:UP000184440};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FRCS01000008; SHN42480.1; -; Genomic_DNA.
DR RefSeq; WP_073260460.1; NZ_FRCS01000008.1.
DR AlphaFoldDB; A0A1M7R8L1; -.
DR STRING; 134849.SAMN05443668_108223; -.
DR OrthoDB; 5296884at2; -.
DR Proteomes; UP000184440; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd07067; HP_PGM_like; 1.
DR CDD; cd09279; RNase_HI_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR014636; RNaseH/PGlycerate_mutase.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR48100; BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED; 1.
DR PANTHER; PTHR48100:SF1; PHOSPHOGLYCERATE MUTASE PMU1-RELATED; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR Pfam; PF13456; RVT_3; 1.
DR PIRSF; PIRSF036922; RNaseH_PGAM; 1.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000184440}.
FT DOMAIN 2..134
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT REGION 162..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 230
FT /note="Tele-phosphohistidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT ACT_SITE 304
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT BINDING 280
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
SQ SEQUENCE 424 AA; 44224 MW; 4E3C480AB41C3660 CRC64;
MSVEHVVVEA DGGSRGNPGP AGYGAVVLDP ETGIVLAERA KALGVTTNNV AEYSGLIAGL
EAAQALGARR VDVRMDSKLV IEQCSGRWQV KQPHLRPLVS RATALLGSFE ATTMTWIPRA
QNKAADALAN AAMDGEDIAR DHAAVAPATD DASGAAATLF DADGPAAESG SRDTAGVSGT
DPTATAPAEA LRGTPAQDRP AVAPRHASIK NAGPGWGPQR RATTTVLVRH ASSVLSPEKR
FSGRGDVPLS EDGVAQAERV AARLGARPGL DVVVSSPLRR ARHTAELIAK AAGIELVTDD
DLVETDFGAW EGLTFSEARR ADPAAVDAWL ASPDVAPPGG ESFAQVAERV QQARERLVAD
YAGQTIVVVS HVTPLKTLLR MALEAPPTML YRLQLDVTGV SEVDWYADGP ANVRLVNDAH
HLTG
//
