ID   A0A1M7S733_FERGO        Unreviewed;       171 AA.
AC   A0A1M7S733;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Transcriptional regulator {ECO:0008006|Google:ProtNLM};
GN   ORFNames=SAMN02745226_00581 {ECO:0000313|EMBL:SHN54233.1};
OS   Fervidobacterium gondwanense DSM 13020.
OC   Bacteria; Thermotogota; Thermotogae; Thermotogales; Fervidobacteriaceae;
OC   Fervidobacterium.
OX   NCBI_TaxID=1121883 {ECO:0000313|EMBL:SHN54233.1, ECO:0000313|Proteomes:UP000184207};
RN   [1] {ECO:0000313|EMBL:SHN54233.1, ECO:0000313|Proteomes:UP000184207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13020 {ECO:0000313|EMBL:SHN54233.1,
RC   ECO:0000313|Proteomes:UP000184207};
RA   Song W.-J., Kurnit D.M.;
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FRDJ01000002; SHN54233.1; -; Genomic_DNA.
DR   RefSeq; WP_072758130.1; NZ_FRDJ01000002.1.
DR   AlphaFoldDB; A0A1M7S733; -.
DR   STRING; 1121883.SAMN02745226_00581; -.
DR   OrthoDB; 9792661at2; -.
DR   Proteomes; UP000184207; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0036094; F:small molecule binding; IEA:InterPro.
DR   Gene3D; 3.30.1340.20; 3H domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR035922; 3H_dom_sf.
DR   InterPro; IPR004173; 3H_domain.
DR   InterPro; IPR013196; HTH_11.
DR   InterPro; IPR026043; NadR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR40068; TRANSCRIPTION REPRESSOR NIAR-RELATED; 1.
DR   PANTHER; PTHR40068:SF1; TRANSCRIPTION REPRESSOR NIAR-RELATED; 1.
DR   Pfam; PF02829; 3H; 1.
DR   Pfam; PF08279; HTH_11; 1.
DR   PIRSF; PIRSF037847; NiaR; 1.
DR   SUPFAM; SSF75500; Putative transcriptional regulator TM1602, C-terminal domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR037847-1};
KW   Nickel {ECO:0000256|PIRSR:PIRSR037847-1}.
FT   DOMAIN          3..55
FT                   /note="Helix-turn-helix type 11"
FT                   /evidence="ECO:0000259|Pfam:PF08279"
FT   DOMAIN          67..159
FT                   /note="3H"
FT                   /evidence="ECO:0000259|Pfam:PF02829"
FT   BINDING         71
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         79
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         138
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         140
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
SQ   SEQUENCE   171 AA;  19442 MW;  12B7BEA0EABFBA25 CRC64;
     MERKYQILEV LKKSKTPIKG KDLSEMFNVS RQMIVSDIAE LREEGYKIVS TRDGYVFDHG
     NTVRRVIAVK HNVSDIYDEL KKIVENGGKV LDVIVEHPIY GELTGRIDVG TLDEVEKFVS
     LLASTGTKPL SEISNGIHLH TIEAPDEETM NKILKAIRRY RITKDNEEAT E
//