ID   A0A1M7SAE4_9RHOB        Unreviewed;       624 AA.
AC   A0A1M7SAE4;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Chloride channel protein, CIC family {ECO:0000313|EMBL:SHN55567.1};
GN   ORFNames=SAMN05216200_102145 {ECO:0000313|EMBL:SHN55567.1};
OS   Oceanicella actignis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Oceanicella.
OX   NCBI_TaxID=1189325 {ECO:0000313|EMBL:SHN55567.1, ECO:0000313|Proteomes:UP000184066};
RN   [1] {ECO:0000313|EMBL:SHN55567.1, ECO:0000313|Proteomes:UP000184066}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.10808 {ECO:0000313|EMBL:SHN55567.1,
RC   ECO:0000313|Proteomes:UP000184066};
RA   Song W.-J., Kurnit D.M.;
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FRDL01000002; SHN55567.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1M7SAE4; -.
DR   STRING; 1189325.SAMN04488119_103363; -.
DR   Proteomes; UP000184066; Unassembled WGS sequence.
DR   GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   CDD; cd00400; Voltage_gated_ClC; 1.
DR   Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR014743; Cl-channel_core.
DR   InterPro; IPR001807; Cl-channel_volt-gated.
DR   PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR   PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR   Pfam; PF00654; Voltage_CLC; 1.
DR   PRINTS; PR00762; CLCHANNEL.
DR   SUPFAM; SSF54631; CBS-domain pair; 1.
DR   SUPFAM; SSF81340; Clc chloride channel; 1.
DR   PROSITE; PS51371; CBS; 1.
PE   4: Predicted;
KW   CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184066};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        102..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        147..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        245..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        280..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        320..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        362..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        395..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        427..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        454..479
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        485..502
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          557..617
FT                   /note="CBS"
FT                   /evidence="ECO:0000259|PROSITE:PS51371"
FT   REGION          1..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   624 AA;  64515 MW;  1CB1EF1438B907EB CRC64;
     MGNDEAKARR GLAAAGGDAG NEAGDDMGDD AAGAAPGPSG AAGDGSARGG AGAAAPRARE
     RLRRHARRRA AAALRRGRVA ARRAAVEGWS ALRQRGPGQA QFWLMALFLG LAAGGAAILF
     RLAISQIQTL IYGADDVRLH STLERTHWAV VVGVPVLGGA LVGWILSRFT DDGKARSVAH
     VIEGAALRRG RVELRAGLAS AAASLVTLST GGSSGREGPV VHLAAVISSW VSERIRATPM
     TARDLMGCAV AAAVSASFNA PIAGALFAQE VILRHFALHA YAPIVIASIA GAALGRATMG
     NVTEFVLPPQ SLSFYQELPA FLLLGLVCGL TAVALMRAIF LAEDVGDRAQ ALLRIPAWAR
     PAAAGLLLGL IALRFPHIIG VGYETTSRAL TGALGLREAV LFAVVKAAAV AITFGGRMGG
     GVFSPSLMMG ALTGLAFGTV AVALFPAMSG GQTLYALAGM GAVAAAVLGA PISTTLIVFE
     LTGDWQAGLA VMASVSLSTL VASRMVDRSF FLTQLERRNL HLAEGPHRWA PATIAVRDVM
     RLAGAEDGPS LSAAQALIEQ GAVLRMDDTL ERALPMFARH SGPMLPVVAE GEDGRPELIG
     AVFHLDALRA YVRVLEENLR EEHG
//