ID A0A1M7TTG9_9ACTN Unreviewed; 462 AA.
AC A0A1M7TTG9;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain {ECO:0000313|EMBL:SHN74044.1};
GN ORFNames=SAMN05443668_1073 {ECO:0000313|EMBL:SHN74044.1};
OS Cryptosporangium aurantiacum.
OC Bacteria; Actinomycetota; Actinomycetes; Cryptosporangiales;
OC Cryptosporangiaceae; Cryptosporangium.
OX NCBI_TaxID=134849 {ECO:0000313|EMBL:SHN74044.1, ECO:0000313|Proteomes:UP000184440};
RN [1] {ECO:0000313|EMBL:SHN74044.1, ECO:0000313|Proteomes:UP000184440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 46144 {ECO:0000313|EMBL:SHN74044.1,
RC ECO:0000313|Proteomes:UP000184440};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; FRCS01000007; SHN74044.1; -; Genomic_DNA.
DR RefSeq; WP_073259829.1; NZ_FRCS01000007.1.
DR AlphaFoldDB; A0A1M7TTG9; -.
DR STRING; 134849.SAMN05443668_1073; -.
DR OrthoDB; 9802328at2; -.
DR Proteomes; UP000184440; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF2; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:SHN74044.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:SHN74044.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000184440};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:SHN74044.1}.
FT DOMAIN 4..70
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 462 AA; 48609 MW; FAFE01DC05C5BF16 CRC64;
MYDGSSTAHL VEALRTALNR YSVGEKLPSS RALVRQYEVS PVTVARAIAA LVAEGLVTSR
PGAGVFKANR AERGVPGDVS WQEVALSADA GARGVDAAGV LATLTAPPAE VVDLNGGYLH
TSLQPERALA AALARAGRRP GAWSRPPVEG LPELRSWFAR DIGGSLDGGD VLVTAGGQTA
LTTALRALAV PGAPVLVESP TYPGLLAVAR AAGLRPVPVP VDADGVRTDL LADAFAATRA
RLFVCQPLFQ NPTGTVLAPV RRAEVVRIAH TAGAFVVEDD FARRLVHADA PPLPPPLAAD
DPDGVVVHVR SLTKVTSPSL RIGALTARGP ALERLRATQI VDSFFVPRPL QETALELVGS
PAWARHLRTL AVALRDRRTA LLGALADLRP QWTPYGGYHL WLRLPDGTDE QAVVAAALRE
GVAVTPGGSY FTAEAPGPYL RLSYVSTAHP EDGGHRLRRA LR
//
