ID A0A1M7Y4B3_9FIRM Unreviewed; 349 AA.
AC A0A1M7Y4B3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family {ECO:0000313|EMBL:SHO47120.1};
GN ORFNames=SAMN02745217_01424 {ECO:0000313|EMBL:SHO47120.1};
OS Anaerocolumna xylanovorans DSM 12503.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Anaerocolumna.
OX NCBI_TaxID=1121345 {ECO:0000313|EMBL:SHO47120.1, ECO:0000313|Proteomes:UP000184612};
RN [1] {ECO:0000313|EMBL:SHO47120.1, ECO:0000313|Proteomes:UP000184612}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12503 {ECO:0000313|EMBL:SHO47120.1,
RC ECO:0000313|Proteomes:UP000184612};
RA Song W.-J., Kurnit D.M.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FRFD01000004; SHO47120.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M7Y4B3; -.
DR STRING; 1121345.SAMN02745217_01424; -.
DR OrthoDB; 9801456at2; -.
DR Proteomes; UP000184612; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd03360; LbH_AT_putative; 1.
DR CDD; cd06849; lipoyl_domain; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR020019; AcTrfase_PglD-like.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR001451; Hexapep.
DR InterPro; IPR018357; Hexapep_transf_CS.
DR InterPro; IPR041561; PglD_N.
DR InterPro; IPR011053; Single_hybrid_motif.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR NCBIfam; TIGR03570; NeuD_NnaD; 1.
DR PANTHER; PTHR43300; ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR43300:SF7; UDP-N-ACETYLBACILLOSAMINE N-ACETYLTRANSFERASE; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF00132; Hexapep; 1.
DR Pfam; PF17836; PglD_N; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:SHO47120.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000184612};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SHO47120.1}.
FT DOMAIN 3..77
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
FT ACT_SITE 286
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
FT SITE 287
FT /note="Increases basicity of active site His"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
SQ SEQUENCE 349 AA; 37708 MW; 6C9A54440C654F6C CRC64;
MSKFEILMPR LGTNDNFVTI GLWNVKNGDM VKAGQIIAII ETTKETQDLE AEKDGYIYLK
YVEGDDVEVG KVIAYISAEK EELNEEKTSS TVAQLNITKK ALELAEKNGI DLSKLDSSKM
IREKDILVLL GEKKVSKRNI ANDVIIVSGG GVAKMCIDIL RESKNYNIAG ITDIKLKTGN
EVMGVPVLGN DDILDELKDK GYMLAVNAIG GIANDNTGKL FFLRENMYNI IKSKGFFMPN
IIHPNAFIES SAELGEGNLL LAGAIVGSDV KIGNDCIINT GAIVSHDCII EDHAKISPGA
ILAGNVQIGE NSLIGMGVTI YIGVKIGKNV IISNGKNIFS DVPDNSIIM
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