ID A0A1M7Y991_9FIRM Unreviewed; 387 AA.
AC A0A1M7Y991;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|PROSITE:PS51918};
GN ORFNames=SAMN02745217_02125 {ECO:0000313|EMBL:SHO49098.1};
OS Anaerocolumna xylanovorans DSM 12503.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Anaerocolumna.
OX NCBI_TaxID=1121345 {ECO:0000313|EMBL:SHO49098.1, ECO:0000313|Proteomes:UP000184612};
RN [1] {ECO:0000313|EMBL:SHO49098.1, ECO:0000313|Proteomes:UP000184612}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12503 {ECO:0000313|EMBL:SHO49098.1,
RC ECO:0000313|Proteomes:UP000184612};
RA Song W.-J., Kurnit D.M.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the radical SAM superfamily. Anaerobic
CC sulfatase-maturating enzyme family. {ECO:0000256|ARBA:ARBA00023601}.
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DR EMBL; FRFD01000006; SHO49098.1; -; Genomic_DNA.
DR RefSeq; WP_073588837.1; NZ_FRFD01000006.1.
DR AlphaFoldDB; A0A1M7Y991; -.
DR STRING; 1121345.SAMN02745217_02125; -.
DR OrthoDB; 1994517at2; -.
DR Proteomes; UP000184612; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023867; Sulphatase_maturase_rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR43273; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR PANTHER; PTHR43273:SF8; RADICAL SAM PROTEIN-RELATED; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDG01216; thioether_bond_formation_requi; 1.
DR SFLD; SFLDG01384; thioether_bond_formation_requi; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000184612};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 1..222
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 387 AA; 45888 MW; 7444271E494E86FF CRC64;
MSYTIYLTTD CNFKCSYCYE NYKQQLQLSK DRLINTINFI FHYDNSKKIL LDFLGGEPLL
KKNLIYQAVN YIEEQYPDRI VKYYITTNCS LMDDDFIKFM KKNNFDIRLS FDGTEKAHNL
NRIPRNNEFC YEKIFQNIKK VRDSGMQYSV RMTITNETIP HMFQNIKFLH ENGLNNICMI
PDVYLKFSKN SLAEFKNQVE KITDYYIQEY SQERKFSIDQ YDGKFLNILC DFGNHFSMCD
AGISNFKIMP DGKIYPCGFL TDNEKYVIGD IHEESIDIRR GKMVALSHYD KSDNKCKDCK
IRDFCHGMKC GYMNLIRTGS INIPDDSVCQ YEHVFYPEVL KVLMYLSDNP DAEIKQRLNG
FMQYIEQDSL RLSEMGIQIQ KKMRICR
//
