ID A0A1M7Z705_9BACT Unreviewed; 1075 AA.
AC A0A1M7Z705;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Tricorn protease homolog {ECO:0000256|PIRNR:PIRNR036421};
DE EC=3.4.21.- {ECO:0000256|PIRNR:PIRNR036421};
GN ORFNames=SAMN04488108_0934 {ECO:0000313|EMBL:SHO60649.1};
OS Algoriphagus zhangzhouensis.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC Algoriphagus.
OX NCBI_TaxID=1073327 {ECO:0000313|EMBL:SHO60649.1, ECO:0000313|Proteomes:UP000184609};
RN [1] {ECO:0000313|Proteomes:UP000184609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25035 {ECO:0000313|Proteomes:UP000184609};
RA Varghese N., Submissions S.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Degrades oligopeptides. {ECO:0000256|PIRNR:PIRNR036421}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|PIRNR:PIRNR036421}.
CC -!- SIMILARITY: Belongs to the peptidase S41B family.
CC {ECO:0000256|ARBA:ARBA00008524, ECO:0000256|PIRNR:PIRNR036421}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FRXN01000001; SHO60649.1; -; Genomic_DNA.
DR RefSeq; WP_073570555.1; NZ_SORH01000001.1.
DR AlphaFoldDB; A0A1M7Z705; -.
DR STRING; 1073327.SAMN04488108_0934; -.
DR OrthoDB; 9815657at2; -.
DR Proteomes; UP000184609; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-UniRule.
DR CDD; cd07562; Peptidase_S41_TRI; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.750.44; -; 1.
DR Gene3D; 2.120.10.60; Tricorn protease N-terminal domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR005151; Tail-specific_protease.
DR InterPro; IPR028204; Tricorn_C1.
DR InterPro; IPR029414; Tricorn_PDZ.
DR InterPro; IPR012393; Tricorn_protease.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR43253; TRICORN PROTEASE HOMOLOG 2-RELATED; 1.
DR PANTHER; PTHR43253:SF1; TRICORN PROTEASE HOMOLOG 2-RELATED; 1.
DR Pfam; PF07676; PD40; 4.
DR Pfam; PF03572; Peptidase_S41; 1.
DR Pfam; PF14684; Tricorn_C1; 1.
DR Pfam; PF14685; Tricorn_PDZ; 1.
DR PIRSF; PIRSF036421; Tricorn_protease; 1.
DR SMART; SM00245; TSPc; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF69322; Tricorn protease domain 2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR036421};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR036421};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PIRNR:PIRNR036421};
KW Reference proteome {ECO:0000313|Proteomes:UP000184609};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW ECO:0000256|PIRNR:PIRNR036421}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1075
FT /note="Tricorn protease homolog"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012432746"
FT DOMAIN 832..1026
FT /note="Tail specific protease"
FT /evidence="ECO:0000259|SMART:SM00245"
FT REGION 534..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..557
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 733
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR036421-1"
FT ACT_SITE 957
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR036421-1"
FT ACT_SITE 1015
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR036421-1"
SQ SEQUENCE 1075 AA; 120299 MW; 3462F7C372B3EDCA CRC64;
MKKLLFPFLA LGISSLTMGQ STQLLRQPTL SQTEIVFVYA DDLWKVSRNG GAASRLTSNE
GEESYPHFSP DGKWIAFTGE YDGNTDVYLI ASDGSEPKRL TWHPGNDQVT GWSPDGKKVL
FASGRESHPT QESKFYEISI NGGMPEALAI PRAVNGEISP DGSKIAYQQI AFWDPEWRNH
RGGQAKPIWV VDLKNYNLTM SPQLDGERQT DPVWLGNKVF YISERDYLAN LWSFDPSTGV
EKQETFLKDF DIKNIDAGPD AIVIEQGGYL HLYNPADQTL KQVPIEVKGD FFWARERWVD
VSANQLLNPQ LSPTGQRAIF EFRGEIITIP KENGAGRNIT NSSASAERAP IWSPDGNHIA
YFSDASGEYQ LMVSDQTGSK IEKTISIPDP SFFFKPEWSP NGKYISFTDT DYNIWIVEYE
SGSAKIVETD RFAHPDRTMN PVWSPDGKWI AYSRLMDNQF KSIFVYNAET GKKIQVTDSM
ADAITPVWDE SGKYLYYLAS TDYGLSSGWL DMSSYDHPVN RTLYLTVLNS KDSSPLLPKS
DEEIEKEKDS SKDEEKETII DEAGIMERIV AIDLPARNYT GLAPGPSGTV FYMESILNEG
TILKKFDLTK RKSDDFLPRV NQVVVSKDRK SLLYQSGSTW GIVETSGVGK KSGDGSLKAL
SSMKIKVNPQ QEWQQIYREG WRYQRDFLYV DNVHGAPWDE IYQWYKPWVS SVRHRSDMNY
IIDIIGGEVA VGHSYTRGGD FPDVKRVPIG LLGADFELDK GNYKIKKIYN GESWNPNLSA
PLAQPGNSAK VGEYIVAING KEIQPGTNIY SYLEGTANQY TQIQVNTKPG LDGARLIGTI
PVTNENQLRL MDWVEGNRRK VDELSDGKIA YVYLPNTGGP GYTFFNRYYF SQQDKKGAVI
DERNNGGGSA ADYMVDIMAR KLQGYFNSRA NDHRPFTTPI AGIWGPKVML INGRAGSGGD
LLPYLFHQME IGPLVGVKTW GGLVGTWDTP PFIDGGRMVA PRGGFYDLNG EWAVEGVGIS
PDIPVEQTPK DVIAGKDPQL ERAVKEALDR MATEGVELMP EPAPPIRYFR PKKGN
//
