ID A0A1M8A111_MALS4 Unreviewed; 817 AA.
AC A0A1M8A111;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Similar to S.cerevisiae protein MSH1 (DNA-binding protein of the mitochondria) {ECO:0000313|EMBL:SHO75884.1};
GN ORFNames=MSYG_0217 {ECO:0000313|EMBL:SHO75884.1};
OS Malassezia sympodialis (strain ATCC 42132) (Atopic eczema-associated
OS yeast).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX NCBI_TaxID=1230383 {ECO:0000313|EMBL:SHO75884.1, ECO:0000313|Proteomes:UP000186303};
RN [1] {ECO:0000313|Proteomes:UP000186303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42132 {ECO:0000313|Proteomes:UP000186303};
RX PubMed=28100699; DOI=10.1093/nar/gkx006;
RA Zhu Y., Engstroem P.G., Tellgren-Roth C., Baudo C.D., Kennell J.C., Sun S.,
RA Billmyre R.B., Schroeder M.S., Andersson A., Holm T., Sigurgeirsson B.,
RA Wu G., Sankaranarayanan S.R., Siddharthan R., Sanyal K., Lundeberg J.,
RA Nystedt B., Boekhout T., Dawson T.L. Jr., Heitman J., Scheynius A.,
RA Lehtioe J.;
RT "Proteogenomics produces comprehensive and highly accurate protein-coding
RT gene annotation in a complete genome assembly of Malassezia sympodialis.";
RL Nucleic Acids Res. 45:2629-2643(2017).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
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DR EMBL; LT671821; SHO75884.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M8A111; -.
DR STRING; 1230383.A0A1M8A111; -.
DR VEuPathDB; FungiDB:MSYG_0217; -.
DR OMA; DTWIMRR; -.
DR Proteomes; UP000186303; Chromosome 1.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 3.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:SHO75884.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000186303}.
FT DOMAIN 678..694
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 817 AA; 92128 MW; D8C2D1422F72D785 CRC64;
MAGFPIHQLD KYLKVLVQEH GNLVAICEEF KAEAKNVPFQ RRVTRVVSPG TLIDERFLDP
FHNNFILAIF ESEGGTFGLA WLDVSTADFQ TTESSDPKTV RDEITRIAPR EVVLVHDNIY
PPDHPIAEAI SRTQALISHT PMPEQTSESL GIEKTSVSAA EHSAIRLLTG YLSTRLLEHM
PDMHVDTPQH SETTMHMDAA TLTALEIRET NERSTRGSLI KILRRTVTQG GARLLVHWLT
SPSTSIPLIQ ARQSMVDLFL KNSFLRQDIR MIMHTSIGDI LRTLQRVSLR RNDVQDLLKI
RDFIRATDQI LDRLERETSA PIGGLELQEW MRRCTSLDEL GDRLGNAIDE RVMQKRLEQQ
AALIKQFDSM YDTGEATTES IDVPKVRKQR RSSVSIPLLL EGPLWGDDIE HLVRPDSSPM
LQNLTDQYNG YRVKARILEN SLRERHGEYV TLKFLLGQGY IVHFSSPRGD ELDENLTLAY
KTKTTRTFYH PEWSKIGMKL QKLKEGISDC ESRLLDTLRL EVLAHSDKLR RNARLLDQLD
VLQSFAQAAE ELSLVRPVID NSSQLDICDG RHLGVELGLM EQERLFTKNH LKLGQDARLH
LITGPNMGGK STFLRQNAII AVLAQAGSFV PAEAARIGIV DAIFSRVGAK DDLFHNRSTF
MVEMSETADI LQRATSRSFV IADEIGRGTN TSVGLAVAFS VLHSLAIRTQ CRTLFATHYY
ELADMLGFDQ DQPPSQALSD QVAFFCTRLE KHGDVLWFSH RVRPGVNRDS HGLDIARLAG
MPKDTMELAA KTHAWIVQHG RANIDTRGLV QDVLVSQ
//
