ID A0A1M8AA42_MALS4 Unreviewed; 542 AA.
AC A0A1M8AA42;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Similar to S.cerevisiae protein CDC20 (Activator of anaphase-promoting complex/cyclosome (APC/C)) {ECO:0000313|EMBL:SHO79054.1};
GN ORFNames=MSYG_3403 {ECO:0000313|EMBL:SHO79054.1};
OS Malassezia sympodialis (strain ATCC 42132) (Atopic eczema-associated
OS yeast).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX NCBI_TaxID=1230383 {ECO:0000313|EMBL:SHO79054.1, ECO:0000313|Proteomes:UP000186303};
RN [1] {ECO:0000313|Proteomes:UP000186303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42132 {ECO:0000313|Proteomes:UP000186303};
RX PubMed=28100699; DOI=10.1093/nar/gkx006;
RA Zhu Y., Engstroem P.G., Tellgren-Roth C., Baudo C.D., Kennell J.C., Sun S.,
RA Billmyre R.B., Schroeder M.S., Andersson A., Holm T., Sigurgeirsson B.,
RA Wu G., Sankaranarayanan S.R., Siddharthan R., Sanyal K., Lundeberg J.,
RA Nystedt B., Boekhout T., Dawson T.L. Jr., Heitman J., Scheynius A.,
RA Lehtioe J.;
RT "Proteogenomics produces comprehensive and highly accurate protein-coding
RT gene annotation in a complete genome assembly of Malassezia sympodialis.";
RL Nucleic Acids Res. 45:2629-2643(2017).
CC -!- SIMILARITY: Belongs to the WD repeat CDC20/Fizzy family.
CC {ECO:0000256|ARBA:ARBA00006445}.
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DR EMBL; LT671825; SHO79054.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M8AA42; -.
DR STRING; 1230383.A0A1M8AA42; -.
DR VEuPathDB; FungiDB:MSYG_3403; -.
DR OMA; CSGACLN; -.
DR Proteomes; UP000186303; Chromosome 5.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IEA:InterPro.
DR GO; GO:0097027; F:ubiquitin-protein transferase activator activity; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR033010; Cdc20/Fizzy.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19918; CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED; 1.
DR PANTHER; PTHR19918:SF68; FI02843P; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000186303};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 251..307
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 256..290
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 340..372
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 476..509
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 19..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 88..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 542 AA; 58056 MW; A37B0D5F04FEA0FA CRC64;
MSLESPLADV PTNIRSRLTA SPLHLGGKGL RTGAPAASTR RDKEDLFPGV PGDMEMRGVV
AKDWDGPDVN LTRRRGSAMV SRGDRYIPNR DLLRTGGTTP FLEDSAGDTL SRRSSSETTA
SSSDSHAAAD LEPAPALEGV CQVDLGQRIL SFSAVPPSAS HAKDLRARYA PKPKSTLPSS
LLAAGRRRVP TAPERVLDAP AIVPDFYVNL LHWSSQNMIA IALQSAVYAW NSETGETQML
MDLDDENERV GGGGLVTSLQ WDAHGNILAI GTDRGYTQIW DAARGARLRT LRPSAEGGAD
AAAVNVAAWA VDGTLSLGYA SGLLREHDVR QRASETRSLE HAHAAQVCGL SWREDSALLA
SGGNDNVVKV WDRRTHVPKM RKENHRAAVK ALAWSPHNSS LLATGGGSAD RCIHFWNTTQ
NTRVQTIQTG AQITSLQWAP HYREIVSAHG VSQAENGTGA LCIWAHPSGQ KVADVPGAHD
GRILHSSLSP DGQTLATVGS DESLKFWRLF EQTADSAKAA QQRGVLSGYK GLARTAPARS
LR
//
