ID A0A1N1BAJ2_9MYCO Unreviewed; 337 AA.
AC A0A1N1BAJ2;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=5'-3' exonuclease {ECO:0000313|EMBL:SHT34703.1};
DE EC=2.7.7.7 {ECO:0000313|EMBL:SHT34703.1};
GN Name=polA_1 {ECO:0000313|EMBL:SHT34703.1};
GN Synonyms=polA_3 {ECO:0000313|EMBL:SHZ19172.1};
GN ORFNames=SAMEA2070793_03712 {ECO:0000313|EMBL:SHZ19172.1},
GN SAMEA2259684_01878 {ECO:0000313|EMBL:SHT34703.1}, SAMEA2275847_01536
GN {ECO:0000313|EMBL:SKT87013.1};
OS Mycobacteroides abscessus subsp. abscessus.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacteroides; Mycobacteroides abscessus.
OX NCBI_TaxID=1185650 {ECO:0000313|EMBL:SHT34703.1, ECO:0000313|Proteomes:UP000185014};
RN [1] {ECO:0000313|Proteomes:UP000184807, ECO:0000313|Proteomes:UP000185014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1121 {ECO:0000313|EMBL:SKT87013.1,
RC ECO:0000313|Proteomes:UP000190129}, 425 {ECO:0000313|EMBL:SHZ19172.1,
RC ECO:0000313|Proteomes:UP000184807}, and 879
RC {ECO:0000313|EMBL:SHT34703.1, ECO:0000313|Proteomes:UP000185014};
RG Pathogen Informatics;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FSBZ01000117; SHT34703.1; -; Genomic_DNA.
DR EMBL; FSFZ01000003; SHZ19172.1; -; Genomic_DNA.
DR EMBL; FVNB01000034; SKT87013.1; -; Genomic_DNA.
DR STRING; 36809.BAB79_11060; -.
DR eggNOG; COG0258; Bacteria.
DR Proteomes; UP000184807; Unassembled WGS sequence.
DR Proteomes; UP000185014; Unassembled WGS sequence.
DR Proteomes; UP000190129; Unassembled WGS sequence.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09898; H3TH_53EXO; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SMART; SM00279; HhH2; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Exonuclease {ECO:0000313|EMBL:SHT34703.1};
KW Hydrolase {ECO:0000313|EMBL:SHT34703.1};
KW Nuclease {ECO:0000313|EMBL:SHT34703.1};
KW Nucleotidyltransferase {ECO:0000313|EMBL:SHT34703.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000185014};
KW Transferase {ECO:0000313|EMBL:SHT34703.1}.
FT DOMAIN 12..303
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 337 AA; 35502 MW; A75C8BA95A71AA62 CRC64;
MSEDPARTVP ARPVLLLDGA SLWFRSYFGV PDSITSPDGR PVNAVRGFLD TVSQLITLYR
PHRLAVCLDL DWRPAWRVAA IPSYKAHRVV TDDPLAGRPS DTVGAQTVDI EEVPDELTPQ
VDMIADILDA FGIASAGAAG FEADDVLGTL AANERRDPVI VVSGDRDLLQ VVADVPVPVR
VFYMGRGFAK ATLFGPTEVA EQYGVPLARA GAAYAELALL RGDPSDGLPG VPGVGEKTAA
KLLAEFGSLD GILTAADDPK SGLAKAVRAK LQAATVYMAA AEPVVRVAVD APVIVDRDSD
ALPLTARDPR RVAELGAELG IGSAVTRLQK ALDGLPR
//
