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Database: UniProt
Entry: A0A1N6DHV6_9GAMM
LinkDB: A0A1N6DHV6_9GAMM
Original site: A0A1N6DHV6_9GAMM 
ID   A0A1N6DHV6_9GAMM        Unreviewed;       432 AA.
AC   A0A1N6DHV6;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   16-JAN-2019, entry version 14.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=SAMN05443662_0161 {ECO:0000313|EMBL:SIN70391.1};
OS   Sulfurivirga caldicuralii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales;
OC   Piscirickettsiaceae; Sulfurivirga.
OX   NCBI_TaxID=364032 {ECO:0000313|EMBL:SIN70391.1, ECO:0000313|Proteomes:UP000198461};
RN   [1] {ECO:0000313|EMBL:SIN70391.1, ECO:0000313|Proteomes:UP000198461}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17737 {ECO:0000313|EMBL:SIN70391.1,
RC   ECO:0000313|Proteomes:UP000198461};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; FSRE01000001; SIN70391.1; -; Genomic_DNA.
DR   Proteomes; UP000198461; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000198461};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198461}.
FT   DOMAIN      129    260       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      340    409       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     137    144       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   432 AA;  48950 MW;  737E49EC0A99ACC6 CRC64;
     MQFFTWIRPL EVKEEGNTLR LIAPTSHMQD WINRKLLPQI RAAVAQVKPQ NPPEVVVEVG
     GDYNLAAEPA PQNARPAGGA AVVEVEKPKT AGIRHNLNPA FTFENFVEGK ANQLAAAAAR
     QVAENPGGSY NPFFIYGGVG LGKTHLMHAI GNAMLKNNPD ARVVYLHSER FVADMVNALR
     HNKIDQFKRF YRSLDALLID DIQFFANKEQ SQEEFFHTFN TLLEGNKQVI LTSDRFPKEV
     DGLEDRLKSR FGWGLTIQVE PPEFEMRVAI LLQKAAEADV RLPEEVAFFI AKRLRGNVRD
     LEGALKRVIA YAQFTQQPIT LELAKDALKD LLRIQEKRIT LENIQKTVAD YYKLPIRELL
     SKRRSRNVAR PRQMAMALAK ELTSHSLPEI GDAFGGRDHT TVLHAVRQMK KLRSEDARLE
     EDFNNLIKIL TN
//
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