ID A0A1N6ELB7_9LACT Unreviewed; 458 AA.
AC A0A1N6ELB7;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Putative tyrosine permease, NhaC family {ECO:0000313|EMBL:SIN83701.1};
GN ORFNames=SAMN05878443_0057 {ECO:0000313|EMBL:SIN83701.1};
OS Carnobacterium alterfunditum.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC Carnobacterium.
OX NCBI_TaxID=28230 {ECO:0000313|EMBL:SIN83701.1, ECO:0000313|Proteomes:UP000184758};
RN [1] {ECO:0000313|EMBL:SIN83701.1, ECO:0000313|Proteomes:UP000184758}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=313 {ECO:0000313|EMBL:SIN83701.1,
RC ECO:0000313|Proteomes:UP000184758};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NhaC Na(+)/H(+) (TC 2.A.35) antiporter
CC family. {ECO:0000256|ARBA:ARBA00038435}.
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DR EMBL; FSRN01000001; SIN83701.1; -; Genomic_DNA.
DR RefSeq; WP_034546436.1; NZ_FSRN01000001.1.
DR AlphaFoldDB; A0A1N6ELB7; -.
DR STRING; 28230.SAMN05878443_0057; -.
DR eggNOG; COG1757; Bacteria.
DR OrthoDB; 9762978at2; -.
DR Proteomes; UP000184758; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR InterPro; IPR004770; Na/H_antiport_NhaC.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR NCBIfam; TIGR00931; antiport_nhaC; 1.
DR PANTHER; PTHR33451; MALATE-2H(+)/NA(+)-LACTATE ANTIPORTER; 1.
DR PANTHER; PTHR33451:SF6; NA(+)_H(+) ANTIPORTER NHAC; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 3: Inferred from homology;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 9..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 31..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 158..447
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 458 AA; 49308 MW; 4177C07E11CA6F1E CRC64;
MKKLSIRESF ALLILLLMMI GVSIIKFKLD PQTPLLLAIM LLIFWGRFHK YSWDEIHDGI
KKGVKTGIIP MIIFILIGAL ISIWIAAGII PSMMVIGFKL LNPSFFIPSV FLICAVVGTS
IGSAFTTVST IGLAFLGMGT AMGFTPGLVA GAIVSGSVFG DKMSPLSDST NLSAAVAEVD
LFRHIKNLMW TTIPSLILST LLFLFFGMNK ELATTNQVAG LTKVIESNFQ VNWLAAIPII
FIFIFSWKRI PAIPTLLINI ALSIGLLKFN SPTVTLSQIS SYIQEGYVST TGNEIIDALL
SRGGVQSMMW SISLIILALA LGGLLMEFNI IDTVMSPISN ARMSVGNLIL VTALSAIGVN
ALVGEQYLAI VLPGNAFKKT YKQMGLSPLA LSRVLEDAGA VINSMIPWGV SGVFISTALG
VPTLTYLPYA FFCLLCPVLT VISGFTNIGI KKLEPTKL
//
