ID A0A1N6EPG3_9LACT Unreviewed; 392 AA.
AC A0A1N6EPG3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Concentrative nucleoside transporter, CNT family {ECO:0000313|EMBL:SIN84936.1};
GN ORFNames=SAMN05878443_0120 {ECO:0000313|EMBL:SIN84936.1};
OS Carnobacterium alterfunditum.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC Carnobacterium.
OX NCBI_TaxID=28230 {ECO:0000313|EMBL:SIN84936.1, ECO:0000313|Proteomes:UP000184758};
RN [1] {ECO:0000313|EMBL:SIN84936.1, ECO:0000313|Proteomes:UP000184758}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=313 {ECO:0000313|EMBL:SIN84936.1,
RC ECO:0000313|Proteomes:UP000184758};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the concentrative nucleoside transporter (CNT)
CC (TC 2.A.41) family. {ECO:0000256|ARBA:ARBA00009033}.
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DR EMBL; FSRN01000001; SIN84936.1; -; Genomic_DNA.
DR RefSeq; WP_034546556.1; NZ_FSRN01000001.1.
DR AlphaFoldDB; A0A1N6EPG3; -.
DR STRING; 28230.SAMN05878443_0120; -.
DR eggNOG; COG1972; Bacteria.
DR OrthoDB; 9766455at2; -.
DR Proteomes; UP000184758; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR008276; C_nuclsd_transpt.
DR InterPro; IPR011657; CNT_C_dom.
DR InterPro; IPR002668; CNT_N_dom.
DR InterPro; IPR011642; Gate_dom.
DR PANTHER; PTHR10590; SODIUM/NUCLEOSIDE COTRANSPORTER; 1.
DR PANTHER; PTHR10590:SF4; SOLUTE CARRIER FAMILY 28 MEMBER 3; 1.
DR Pfam; PF07670; Gate; 1.
DR Pfam; PF07662; Nucleos_tra2_C; 1.
DR Pfam; PF01773; Nucleos_tra2_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..21
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 33..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..81
FT /note="Concentrative nucleoside transporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01773"
FT DOMAIN 89..182
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 192..389
FT /note="Concentrative nucleoside transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07662"
SQ SEQUENCE 392 AA; 41294 MW; 29D1CC8EFB021155 CRC64;
MNKLITILGI IVMLGVVYLL SDNKKAINKR TVFTALGAQL VLALFLIKVP LGSWIIEQSA
RAVTKLFSFA NEGLTFVFGD LFGQGYFFID VLGVIIFLSA LTGILSYLGV VGWIVKIIGG
AVGKILGTEK AESFVAVANM FLGQTEAPFL VAKYLPNMTK SELMTVMVSG MGSVSASILV
GYSLLGIPMK WLLITTALVP FGSLLVAKIL TPETEISKVS DVTLNRKGAN TSVFSAMSEG
INNGLQMVLG IGASLIAVIS IVALLNSILG LVGTSFTEAL GYIFLPIGWL MGLNGSEAMI
AGQILGTKMS INEFVAYADL APMMAELSER AVAMLSIAVG SFGAFASIAI CVTGLSVFAP
TRKNDLSKLA LRGMLGGFIV PILSAMFVGL FL
//
