ID A0A1N6FS56_9BURK Unreviewed; 486 AA.
AC A0A1N6FS56;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=DNA-3-methyladenine glycosylase II {ECO:0000313|EMBL:SIN98149.1};
GN ORFNames=SAMN05444165_0363 {ECO:0000313|EMBL:SIN98149.1};
OS Paraburkholderia phenazinium.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=60549 {ECO:0000313|EMBL:SIN98149.1, ECO:0000313|Proteomes:UP000185151};
RN [1] {ECO:0000313|EMBL:SIN98149.1, ECO:0000313|Proteomes:UP000185151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GAS95 {ECO:0000313|EMBL:SIN98149.1,
RC ECO:0000313|Proteomes:UP000185151};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FSRU01000001; SIN98149.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1N6FS56; -.
DR Proteomes; UP000185151; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.10.10; DNA Methylphosphotriester Repair Domain; 1.
DR Gene3D; 3.30.310.20; DNA-3-methyladenine glycosylase AlkA, N-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR035451; Ada-like_dom_sf.
DR InterPro; IPR004026; Ada_DNA_repair_Zn-bd.
DR InterPro; IPR010316; AlkA_N.
DR InterPro; IPR037046; AlkA_N_sf.
DR InterPro; IPR011257; DNA_glycosylase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR PANTHER; PTHR46796:SF2; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR RHAS; 1.
DR PANTHER; PTHR46796; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR RHAS-RELATED; 1.
DR Pfam; PF02805; Ada_Zn_binding; 1.
DR Pfam; PF06029; AlkA_N; 1.
DR Pfam; PF12833; HTH_18; 1.
DR SMART; SM01009; AlkA_N; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SUPFAM; SSF57884; Ada DNA repair protein, N-terminal domain (N-Ada 10); 1.
DR SUPFAM; SSF48150; DNA-glycosylase; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR SUPFAM; SSF55945; TATA-box binding protein-like; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000185151};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 93..191
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
SQ SEQUENCE 486 AA; 53669 MW; A98EA1558DAE8E68 CRC64;
MRYIASMTLD RETCYQAVLS RDRRFDGWFF VAVTSTGIYC RPVCPVRPPK FANCRFYANA
ALAEHAGFRP CLRCRPELAP GHGLLDVSAP LAQAAAALID GGFLNDSNLT ALAARIGVSA
RHLRRIFEAE FGVSPIDYAQ TQRLLLAKRL LTDTTLQAAE IALTAGFGSV RRFNDLFRSR
YGFSPARLRQ RRREAVSTDT FTFELGYRPP FAWDALLYHL TDHAIEGVEQ VTERSYARAV
DIRQDGRHVT GWLQAEDVPS RHALRLTVTA SLTAVLPRLL SQVRHFFDLD CRPDLIDARL
GELAASLPGI RVPGAFDGFE IAVRAIAMRQ WPRADACAWL RRIAETFGAR VTQAPEGLRA
AFATADVLAQ VPAETLRATG LSARGVHLLL KLADDVVQRR VFLEPLTPLE ETLAHLRTEV
GFDEWSVQYI AMRAIGWPNA FPAGDPLSAA SAASAASTDS AAQWAPWRAY AAQHLALVHE
EKAHAA
//
