ID A0A1N6G6B5_9RHOB Unreviewed; 308 AA.
AC A0A1N6G6B5;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=3-hydroxyisobutyrate dehydrogenase {ECO:0000313|EMBL:SIO03063.1};
GN ORFNames=SAMN05444002_2238 {ECO:0000313|EMBL:SIO03063.1};
OS Vannielia litorea.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Vannielia.
OX NCBI_TaxID=1217970 {ECO:0000313|EMBL:SIO03063.1, ECO:0000313|Proteomes:UP000184932};
RN [1] {ECO:0000313|Proteomes:UP000184932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 29440 {ECO:0000313|Proteomes:UP000184932};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FSRL01000001; SIO03063.1; -; Genomic_DNA.
DR RefSeq; WP_074256282.1; NZ_FSRL01000001.1.
DR AlphaFoldDB; A0A1N6G6B5; -.
DR STRING; 1217970.SAMN05444002_2238; -.
DR OrthoDB; 4333at2; -.
DR Proteomes; UP000184932; Unassembled WGS sequence.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR015814; Pgluconate_DH_NAD-bd_C.
DR PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43060:SF15; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF09130; DUF1932; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000184932}.
FT DOMAIN 13..154
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 205..273
FT /note="Phosphogluconate dehydrogenase NAD-binding putative
FT C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09130"
FT ACT_SITE 183
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 308 AA; 32227 MW; 1245F160D81E77DA CRC64;
MPDNKHLSNG PQIVLLGFGE AGQAFASGWK GAGIAVQIAA FDIKTNSPST AEGKWSDYAA
AGVTGVDTLD EVAAQGSLVF SLVTADQAEV AAEAAASSLG PGAWFFDCNS CSPGAKRRNA
QRLEGRGINY IDTAVMAPVH PALHRTPLLL SGPRAGEARD ALHALDMKAA IAGGEVGRAS
ATKMIRSIMV KGIEALTLEC ILAGRRAGVD EAVLASLDAS MPGWNWPQRA AYNLERATTH
GIRRAAEMRE VERTLDELGL PAHMSQAIVE WQALAGSLRL DLNEADADFA ARADLMNDAL
SGAARAAE
//
