ID A0A1N6HR42_9SPHN Unreviewed; 735 AA.
AC A0A1N6HR42;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Capsular exopolysaccharide family {ECO:0000313|EMBL:SIO22149.1};
GN ORFNames=SAMN02745824_3412 {ECO:0000313|EMBL:SIO22149.1};
OS Parasphingorhabdus marina DSM 22363.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Parasphingorhabdus.
OX NCBI_TaxID=1123272 {ECO:0000313|EMBL:SIO22149.1, ECO:0000313|Proteomes:UP000185192};
RN [1] {ECO:0000313|Proteomes:UP000185192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22363 {ECO:0000313|Proteomes:UP000185192};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-
CC [protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:46858,
CC ChEBI:CHEBI:82620, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001074};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the etk/wzc family.
CC {ECO:0000256|ARBA:ARBA00008883}.
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DR EMBL; FSQW01000002; SIO22149.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1N6HR42; -.
DR STRING; 1123272.SAMN02745824_3412; -.
DR Proteomes; UP000185192; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05387; BY-kinase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR025669; AAA_dom.
DR InterPro; IPR032807; GNVR.
DR InterPro; IPR003856; LPS_length_determ_N_term.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005702; Wzc-like_C.
DR NCBIfam; TIGR01007; eps_fam; 1.
DR PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR PANTHER; PTHR32309:SF13; TYROSINE-PROTEIN KINASE ETK-RELATED; 1.
DR Pfam; PF13614; AAA_31; 1.
DR Pfam; PF13807; GNVR; 1.
DR Pfam; PF02706; Wzz; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000185192};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Tyrosine-protein kinase {ECO:0000256|ARBA:ARBA00023137}.
FT TRANSMEM 44..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 32..119
FT /note="Polysaccharide chain length determinant N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02706"
FT DOMAIN 401..470
FT /note="Tyrosine kinase G-rich"
FT /evidence="ECO:0000259|Pfam:PF13807"
FT DOMAIN 548..697
FT /note="AAA"
FT /evidence="ECO:0000259|Pfam:PF13614"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 213..247
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 338..387
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 735 AA; 81265 MW; 100EB3751C3D08E5 CRC64;
MVVEAKNTTS PHNMNQVDVN SDDRRDEQVP LLLQYWQAVS RYRIGIACIV LGTIALGIIV
TLLMTPYYTA TSRIEINRNQ DKVTNVEGLE AEDVGQNLEF YQTQYALLEA RSLADRVVRS
ENLATGDAFF QTFNVDPDEN GIISGSDSRQ SSEDRRRRFE LAIRLLLDNV SISPVRGSSL
VDVSFRSPDP QLSASIANAW VAQFVDSNLD RRFDSTIDAR KFLEERLAQL RARLEDSERR
LVRYADNKEI VTLSTTRDAE GSTVGGDTLI SSNLAALNKA LTDATADRIA AQAQADQNGL
NKDAIENPAI NGMRQKRAEI ASEYAKILVQ FEPEYPTAKA LERQISDLDE SIEKEELRMR
TGALTRYSEA LKRERNLQNQ VAQLKSKFSG ERQDTIQYNI FQREVDTNRQ LYNGLLQRYK
EIGVAGVGSN NIAVVDPALA PEQPSSPRIL LNMALAMLMG LGLAGAYVVV SEQIDQTIKD
PSDLKNRLNL APLGSVPDMR KDDIISMLQD KKSVAWEAYI SIQTSLSFLT SHGAPRSFLM
TSTRPNEGKS TSAFALAAVL SSTNRKVLLI DGDMRNPSLH QMIDQKNVQG LSNYLSGDDD
IDNLIQKMPD QGFWVMTAGP IPPNAAELLS SPRIKKLFDH LEEKFDCVIV DAPPVLGLAD
IPLLANAVEG VIYTIEAGGV KVRGIESALR RVRSSHATIF GAIITKVKSS GTGYGYGYDY
QYSYGQQDPL PAPSA
//
