ID A0A1N6HYY9_9BURK Unreviewed; 820 AA.
AC A0A1N6HYY9;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Small-conductance mechanosensitive channel {ECO:0000313|EMBL:SIO25024.1};
GN ORFNames=SAMN05444165_1692 {ECO:0000313|EMBL:SIO25024.1};
OS Paraburkholderia phenazinium.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=60549 {ECO:0000313|EMBL:SIO25024.1, ECO:0000313|Proteomes:UP000185151};
RN [1] {ECO:0000313|EMBL:SIO25024.1, ECO:0000313|Proteomes:UP000185151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GAS95 {ECO:0000313|EMBL:SIO25024.1,
RC ECO:0000313|Proteomes:UP000185151};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; FSRU01000001; SIO25024.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1N6HYY9; -.
DR OrthoDB; 6500477at2; -.
DR Proteomes; UP000185151; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049142; MS_channel_1st.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR InterPro; IPR045276; YbiO_bact.
DR PANTHER; PTHR30460:SF0; MODERATE CONDUCTANCE MECHANOSENSITIVE CHANNEL YBIO; 1.
DR PANTHER; PTHR30460; UNCHARACTERIZED; 1.
DR Pfam; PF21088; MS_channel_1st; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000185151};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..820
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012726471"
FT TRANSMEM 150..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 562..581
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 566..606
FT /note="Mechanosensitive ion channel transmembrane helices
FT 2/3"
FT /evidence="ECO:0000259|Pfam:PF21088"
FT DOMAIN 608..671
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT REGION 778..820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 820 AA; 86609 MW; CB51460B9C8FD4BB CRC64;
MRTLLVIWLL SLLAAPVFAA PAQPAAASAP PAVTLTPDQA RQALAVLNDP QRRAQIEVTL
HAIAAAGALS APPASAPAAA SAPAAASGAA GTVHAAFESN GLASQLARQG AHGAVQIAGA
VRRSLAALLD VSSVRGWWTD LMNSPQQRTV LGNILLTLLG TLLPALALEW LARRLLRRAI
TALAVRRNVD PRELFLDEPS EATLAAQAAQ AAQAAPADAA GARHAAHHYS LLRRLPRAAL
RMVVRFVPLG VFIGASSLLM SILTDEGTPQ DRALDSIIDI YVLCRVVVIV SGFFLQPDAP
RLRLLQMGTT WAAFTQRWMV IFVSVVGAGS AIADTAVVLG LNEAAHLALM KVVALIGHVM
ISLLILQCRQ PVAARIRARC AASPSLSVIG NALADSWATI GVFVVMALWF VWALDVRNGY
HALLHLGGIS IAVLVAARVV SIVIFGALAR LFDGQDPQTS DSLVHQHAYR YYPLLRRVVS
WTVGIITALV LLQVWGADVS MLFQSGTIGH RLASALVTIA VAAAVALFVW EAANVTVERR
LHQWTNAGDL VRAARLRTLL PMLRSLLFVV IALVVVLTGL SELGVNIGPL LAGASIFGVA
LGFGSQKLVQ DFITGIFLLM ENAMQVGDWV TLAGVSGTVE YLSIRTVRLR GGDGSLYTVP
FSSVSTVNNT NRGLGNAAVK VSILYGQDVD LAIATLKEIG ASLREDPQFK DGILSDFAYW
GIDSVDGSAI TMSGQIQCRD SGRWGVQREF NRRVANLFQA RGIQIANPQR TVMVRSDAQM
GAGKADEGAA VDAEGPNAAD KLDTSAQAAP SPNVAKPPAA
//
