ID A0A1N6IDG1_9BURK Unreviewed; 396 AA.
AC A0A1N6IDG1;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:SIO30052.1};
GN ORFNames=SAMN05444165_2057 {ECO:0000313|EMBL:SIO30052.1};
OS Paraburkholderia phenazinium.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=60549 {ECO:0000313|EMBL:SIO30052.1, ECO:0000313|Proteomes:UP000185151};
RN [1] {ECO:0000313|EMBL:SIO30052.1, ECO:0000313|Proteomes:UP000185151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GAS95 {ECO:0000313|EMBL:SIO30052.1,
RC ECO:0000313|Proteomes:UP000185151};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; FSRU01000001; SIO30052.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1N6IDG1; -.
DR Proteomes; UP000185151; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR012824; CobW.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02475; CobW; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR PANTHER; PTHR13748:SF70; PROTEIN COBW; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000185151}.
FT DOMAIN 298..389
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 396 AA; 43211 MW; B79E00FDB0455C8E CRC64;
MSRLHALPVA ATSFSVPVFR LFNSRAHESA HSFDGITMQN SMRKIPVTVV TGFLGSGKTT
LLRHILQHAG GKRIAVIVNE FGELGIDGEI LKGCGIGCDE EGNETEGQLY ELANGCLCCT
VQEEFFPVME KLVERRDQID HVLIETSGLA LPKPLVQAFN WPAIKNSFTV DAVVTVVDGP
AAASGQFADN PVAVDAQRKA DPNLDHESPL HELFEDQLSA ADLVILNKTD LLDDAQQGAV
EALIREEIPS QVKVVRAHKG QLDLHTLLGL EAASEATIHL RHDHHGSAED ADHHHDEFDS
VVVEAQAPSR EAVIAALQSL VESNTIYRVK GFAALPGAPM RLVIQGVGRR FDSYFDRRWQ
AGETQRSRFV LIGEDLDQAA LQRAFDSALK TEAQQA
//
