ID A0A1N6JY18_9RHOB Unreviewed; 404 AA.
AC A0A1N6JY18;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=23S rRNA m(5)U-1939 methyltransferase {ECO:0000313|EMBL:SIO49234.1};
GN ORFNames=SAMN05444722_2647 {ECO:0000313|EMBL:SIO49234.1};
OS Rhodovulum sp. ES.010.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Rhodovulum.
OX NCBI_TaxID=1882821 {ECO:0000313|EMBL:SIO49234.1, ECO:0000313|Proteomes:UP000184943};
RN [1] {ECO:0000313|EMBL:SIO49234.1, ECO:0000313|Proteomes:UP000184943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ES.010 {ECO:0000313|EMBL:SIO49234.1,
RC ECO:0000313|Proteomes:UP000184943};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RNA M5U methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01024}.
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DR EMBL; FSRS01000001; SIO49234.1; -; Genomic_DNA.
DR RefSeq; WP_074221648.1; NZ_FSRS01000001.1.
DR AlphaFoldDB; A0A1N6JY18; -.
DR STRING; 1882821.SAMN05444722_2647; -.
DR OrthoDB; 9804590at2; -.
DR Proteomes; UP000184943; Unassembled WGS sequence.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 2.40.50.1070; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR030390; MeTrfase_TrmA_AS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR010280; U5_MeTrfase_fam.
DR PANTHER; PTHR11061; RNA M5U METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11061:SF30; TRNA (URACIL(54)-C(5))-METHYLTRANSFERASE; 1.
DR Pfam; PF05958; tRNA_U5-meth_tr; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51687; SAM_MT_RNA_M5U; 1.
DR PROSITE; PS01230; TRMA_1; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01024}; Reference proteome {ECO:0000313|Proteomes:UP000184943};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01024};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01024}.
FT ACT_SITE 358
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10015"
FT ACT_SITE 358
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01024"
FT BINDING 237
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01024"
FT BINDING 264
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01024"
FT BINDING 284
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01024"
FT BINDING 332
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01024"
SQ SEQUENCE 404 AA; 42790 MW; 38B747A0D1E340E1 CRC64;
MVVRLNLRGE GVTAEGVTVP CALPGEEVAG EAEEGRIAAP RILAPVPDRV RAPCPHFARC
GGCTLQHARD GFVASWKTDV VRAALAAHGL EAPVQPILTS PPASRRRAVL SGRRTKSGAL
VGFHARASDQ VVAIPDCRLL HPDLMAALPA CADLTALGAS RKGELALSLT RSEDGVDLAV
AEAKTLDDAL RVALADLARR HDLARLAWNG EIVLTRRPPR QAFGRAHVVT PPGAFLQATE
DGQAALTAAA LEVVADGRRI IDLFAGCGTF TLPLAEAAEV HAAESDAAML AALDSGWRGA
TGLKRVTHEV RDLFRNPVRP EELGRFDAAV LDPPRAGAAA QVAQIAASGL SRLAYVSCNP
VTFARDAKRL CSAGFRLEWV QVVDQFRWSG HVELAAALRR DHMA
//
