ID A0A1N6LW95_BABMR Unreviewed; 2245 AA.
AC A0A1N6LW95;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Cystein Rich Modular Protein, CRMP {ECO:0000313|EMBL:SIO73144.1};
GN ORFNames=BMR1_01G00213 {ECO:0000313|EMBL:SIO73144.1};
OS Babesia microti (strain RI).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Babesiidae; Babesia.
OX NCBI_TaxID=1133968 {ECO:0000313|EMBL:SIO73144.1, ECO:0000313|Proteomes:UP000002899};
RN [1] {ECO:0000313|EMBL:SIO73144.1, ECO:0000313|Proteomes:UP000002899}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RI {ECO:0000313|EMBL:SIO73144.1,
RC ECO:0000313|Proteomes:UP000002899};
RX PubMed=22833609; DOI=10.1093/nar/gks700;
RA Cornillot E., Hadj-Kaddour K., Dassouli A., Noel B., Ranwez V.,
RA Vacherie B., Augagneur Y., Bres V., Duclos A., Randazzo S., Carcy B.,
RA Debierre-Grockiego F., Delbecq S., Moubri-Menage K., Shams-Eldin H.,
RA Usmani-Brown S., Bringaud F., Wincker P., Vivares C.P., Schwarz R.T.,
RA Schetters T.P., Krause P.J., Gorenflot A., Berry V., Barbe V.,
RA Ben Mamoun C.;
RT "Sequencing of the smallest Apicomplexan genome from the human pathogen
RT Babesia microti.";
RL Nucleic Acids Res. 40:9102-9114(2012).
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DR EMBL; FO082871; SIO73144.1; -; Genomic_DNA.
DR VEuPathDB; PiroplasmaDB:BMR1_01G00213; -.
DR OrthoDB; 227622at2759; -.
DR Proteomes; UP000002899; Chromosome I.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00185; TNFRSF; 2.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 6.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR PANTHER; PTHR11319; G PROTEIN-COUPLED RECEPTOR-RELATED; 1.
DR PANTHER; PTHR11319:SF35; OUTER MEMBRANE PROTEIN PMPC-RELATED; 1.
DR Pfam; PF07699; Ephrin_rec_like; 2.
DR SMART; SM01411; Ephrin_rec_like; 10.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR PROSITE; PS01186; EGF_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002899};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1449..1467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1479..1497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1546..1575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1698..1722
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1748..1770
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1782..1801
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1813..1831
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1843..1870
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1876..1896
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1094..1107
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS01186"
FT REGION 2181..2245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2196..2210
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2224..2239
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2245 AA; 254192 MW; B06A4215A232AD66 CRC64;
MEYSDNCNLF YTIQKFDWNT GDKLKHEDPR DYGLDQIIFP FVSEKDKLEI TATTPRGGYY
SMCYLNATNG FGKIIGTAYY VTGYQRDGLF ELYFNENHSS SIFIQSWLTT SKLLSVGLER
YEKGKDKCTG SYVTVGDKIK LFASISLPKE FIGKEFSKEK YKHRIWEIVS LSLPDEEAQF
YNHGGEYTLC GIFDDNTTHS LARGTITPYA KLSFDEFPFH EFGYKDNLSN IFTYNIKKSD
PLSLIWKDHI NCWNPSDSVI FNSCNKKFKH DDWPVNQIGL DMKSVLEDDY NILAFCPRTH
DKYIGLYLVS KNVTPHPIAA FKLPISPTKL QMNIHNGKVT WYVLTYDNKI VSIDQTNLSF
NVSEFKTMTE DRVHAHDFYV IDKFNEPLIL VSDWNSFELK LYNESFSVLA NLTLKGDEFA
TVRPGIIECT TKSDDYVNCF VSHYGTNKID WIFVYENKIQ LGSNYDPLQV PLDSESNGWN
ISSMVAMSLH SPENNILLIH KKNHVYITIL NLDYATKKFS YIGRVKFTDH TKQVIHISSA
LKTTINGKEY NELSVLAICS VTITKHNPMD FRNALEVLPQ NINPYTTDYT TKKYDHPLKI
SQNTKEMAIS RHSIVWFDLK RILEYTINEF NYIGPEWIFE GDNLKYAPTF ITNIGEHWGN
IPIKYTLTPL FKQHEPVATI DPVTGVIYVN LIHTTRLSFE YNVSASNIFG NEKKTLFVVK
TLCPDGHYFG NGGCSLCPIG TYNKSDMSHW NRCIPCPENE TTISSGSFSI NQCLCKPGYH
LEGDDYIQVE GRNDRGCVPC PAGTWKEIVA TKGCFGSGCY PNSSSTVTGS PTDEDRKCEC
FPGYYYHKGA GDVRECKMAE NGYYSNGGYL AKRLECPTNT TSFGIARSVK DCVCRPGYHA
IYNKDGTNLS YIKLKTSILE RHPELVNVQN EINVCIPCGL NKYKSAIGLS GCLDCPANSF
SDSDNAVAKY ECNLCKPGYY ESGNPDDPCR ECPENSFCVG SRPLDTSLQI NSGQFVTCPA
NSSTMPPYYL NTLPIHCVCN EGYEPTGQLS QSGMIECVPV KQGHFKFSSG NTKGLPCPHG
SITQNVGATS QFMCVCPPGF YMMDGKCTPC LMGHFCLGGR DIDGNLIPPQ KCIDENSTTL
NTNATNELDC VCKPGYTRIN PTDKFCKQCP PNHYKSTTSN EACTPCRGHS STGDLRGATS
KEKCFCAPGY YFDKICLPCG KNDIYCPGGK LEIDGLAKTH PPVKCPDNTL ITPGVDVASS
YDDCKCAKGY AFKSLDVQNK TKICEKCPPG TYKSSVSDSG CTGLCPLNST SFLGSQNSKQ
CYCLENFYHV SGGTCLPCPE GSICKGGLVP YAMEKGYDSD FEITSDHHTK PIAMEGYYLD
KLKNTLDVSD DWKFIKCPIE GSCLGKDECL DSMEHYLCAE CKFGYTNNFN KGERCTPCPA
TSVNIGIQFA WYLALLLFNI VIACLNVSAG FNRRSIHSVV IKIALNYCTC MSVLNVINYN
EISLPIQVTN IINAWSRKFS SSKRMYLMSM DCLIRNHYNV SHADSFFYSM MAFALLPIVL
IISVTILMWI ILNLIKIKKH KTIKSKILLL YQAKSHGLDA LASRLIHKYS NERLFLIFRY
ISLPGQNGFV KFLHFLDDMI PIYVTVLFSI HGTITSNMLS LLDCTYINLG KSVPGKYVLR
PAMSVQCSID PSKGYIPYLL LGLGGLLIWG LGIPLISFLV LFTNRKRLHS ADIRRKYGFL
HNGYERSYWF WESVVFARKC LVLVIGSIVI VPSNKLSESR IWLAQGVALT FLILNLIYQP
FDKRDYFALD YLEFYSLISW TFTLFITGFL FDFRLSPISQ IIMITFAVGI NLHFCLSFFK
VLFVSYINYI SLYQKYYAKS FIGAIFRCIG SLSGLWKYKE PIFTYNQHKG EIRVWNEKVS
GHFFSNNISR LELECFSKII ATIYDFCFSS LKLDIISLDF IDFIIRLCIA FPQIEEHLTN
VNKSKGGKDE YLSNLVELEV YDHENNKSDL DLLEKCFNNH LDNLDNVFSD EWANDDAFNV
QFSTKNLGES NSNSDVEQLE TNELKEIVKY LFDDNILLGK LTLSDTYLMI SRLSLIESKL
IIQIYSAYKI AKRLFTDKEI ESQDKLSRKL LALNNKFEDV LSKGISDSEL SDIKEKIIEV
QSRRMQLKNE FDTLRKSSFM SKSDIPQDKG DDSNQQDDSF IQNIRNISIE KKKQATLDDF
SGDSTDELGS EEIESDGYDD TDHDS
//
