ID A0A1N6MTF6_9GAMM Unreviewed; 350 AA.
AC A0A1N6MTF6;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Murein hydrolase activator NlpD {ECO:0000256|ARBA:ARBA00040670};
GN Name=nlpD {ECO:0000313|EMBL:SIP72116.1};
GN ORFNames=XIS1_1350021 {ECO:0000313|EMBL:SIP72116.1};
OS Xenorhabdus innexi.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=290109 {ECO:0000313|EMBL:SIP72116.1, ECO:0000313|Proteomes:UP000196435};
RN [1] {ECO:0000313|Proteomes:UP000196435}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HGB1681 (deposited as PTA-6826 in the American Type Culture
RC Collection) {ECO:0000313|Proteomes:UP000196435};
RA Gaudriault S.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Activator of the cell wall hydrolase AmiC. Required for
CC septal murein cleavage and daughter cell separation during cell
CC division. {ECO:0000256|ARBA:ARBA00037728}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004519}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004519}. Membrane
CC {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004635}.
CC -!- SIMILARITY: Belongs to the E.coli NlpD/Haemophilus LppB family.
CC {ECO:0000256|ARBA:ARBA00038420}.
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DR EMBL; FTLG01000041; SIP72116.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1N6MTF6; -.
DR OrthoDB; 9795421at2; -.
DR Proteomes; UP000196435; Unassembled WGS sequence.
DR CDD; cd00118; LysM; 1.
DR CDD; cd12797; M23_peptidase; 1.
DR Gene3D; 2.70.70.10; Glucose Permease (Domain IIA); 1.
DR Gene3D; 3.10.350.10; LysM domain; 1.
DR InterPro; IPR011055; Dup_hybrid_motif.
DR InterPro; IPR018392; LysM_dom.
DR InterPro; IPR036779; LysM_dom_sf.
DR InterPro; IPR016047; Peptidase_M23.
DR PANTHER; PTHR21666:SF290; MUREIN HYDROLASE ACTIVATOR NLPD; 1.
DR PANTHER; PTHR21666; PEPTIDASE-RELATED; 1.
DR Pfam; PF01476; LysM; 1.
DR Pfam; PF01551; Peptidase_M23; 1.
DR SMART; SM00257; LysM; 1.
DR SUPFAM; SSF51261; Duplicated hybrid motif; 1.
DR PROSITE; PS51782; LYSM; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288, ECO:0000313|EMBL:SIP72116.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Reference proteome {ECO:0000313|Proteomes:UP000196435}.
FT DOMAIN 113..157
FT /note="LysM"
FT /evidence="ECO:0000259|PROSITE:PS51782"
FT REGION 49..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 350 AA; 38246 MW; 30DC46FE09A2CD86 CRC64;
MKVGNLMKKI QWIIIYTIAG TILAGCSNTP NHPAPIVSVD NQEKNRIISS RPSSVSTPMP
SSPPVISKNR ATDNNASNSR YLDNRAGGNS LQQGRIVYNR NYGNIPKGSY NGKTYTVKHG
DTLFYIAWIT GKDFRELSHI NSISEPYGLN VGQVLRIGNV NSINGVSVAS NSTQSKIEQV
DFQKSNAYPA NIDRHNSQKT LPRETISGSD DAPYKASSAA DLNASRPINN WRWPAEGKIL
EGFSDSQGGN KGIDIAGNRG QPVFATASGK VVYAGNALRG YGNLIIIKHD DDYLSAYAHN
DTMLVREQQD VQAGQKIATM GSTGTSSVRL HFEIRYKGKS VNPLRYLPQR
//
