ID   A0A1N6MW64_9GAMM        Unreviewed;       401 AA.
AC   A0A1N6MW64;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Aromatic amino acid permease {ECO:0000256|RuleBase:RU367149};
GN   Name=tyrP {ECO:0000313|EMBL:SIP72979.1};
GN   ORFNames=XIS1_1700030 {ECO:0000313|EMBL:SIP72979.1};
OS   Xenorhabdus innexi.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=290109 {ECO:0000313|EMBL:SIP72979.1, ECO:0000313|Proteomes:UP000196435};
RN   [1] {ECO:0000313|Proteomes:UP000196435}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HGB1681 (deposited as PTA-6826 in the American Type Culture
RC   Collection) {ECO:0000313|Proteomes:UP000196435};
RA   Gaudriault S.;
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in transporting aromatic amino acids across the
CC       cytoplasmic membrane. {ECO:0000256|RuleBase:RU367149}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU367149}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC       ECO:0000256|RuleBase:RU367149}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC       Mtr/TnaB/TyrP permease subfamily. {ECO:0000256|ARBA:ARBA00005452,
CC       ECO:0000256|RuleBase:RU367149}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FTLG01000080; SIP72979.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1N6MW64; -.
DR   OrthoDB; 18749at2; -.
DR   Proteomes; UP000196435; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015173; F:aromatic amino acid transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR018227; Amino_acid_transport_2.
DR   InterPro; IPR013061; Trp/try_permease_CS.
DR   InterPro; IPR013059; Trp_tyr_transpt.
DR   NCBIfam; TIGR00837; araaP; 1.
DR   PANTHER; PTHR46997; LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED; 1.
DR   PANTHER; PTHR46997:SF2; TYROSINE-SPECIFIC TRANSPORT SYSTEM; 1.
DR   Pfam; PF03222; Trp_Tyr_perm; 1.
DR   PRINTS; PR00166; AROAAPRMEASE.
DR   PROSITE; PS00594; AROMATIC_AA_PERMEASE_1; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport {ECO:0000256|ARBA:ARBA00022970,
KW   ECO:0000256|RuleBase:RU367149};
KW   Cell inner membrane {ECO:0000256|ARBA:ARBA00022519,
KW   ECO:0000256|RuleBase:RU367149};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU367149};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU367149};
KW   Reference proteome {ECO:0000313|Proteomes:UP000196435};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU367149};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU367149};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU367149}.
FT   TRANSMEM        7..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        37..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        79..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        118..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        144..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        217..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        273..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        311..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        335..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
FT   TRANSMEM        376..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367149"
SQ   SEQUENCE   401 AA;  42656 MW;  0C805198617103BE CRC64;
     MKNRTIGSIF IVAGTTIGAG MLAMPLAAAG VGFGTTLAML IVLWALMSYT ALLLVEVYQY
     NKANTGLGTI AKRYLGTGGQ VLTGFSMLFL MYALTTAYIS GAGELLAASL SAWLDKQISV
     SVGIIIFTLV AGSVVCISTR SVDLINRLLF TAKVIFLVLV LGVMMPHVDK INLISMPIEK
     GLVLSAIPVI FTSFGFHGSV PSIVAYMGGE TNKLRKIFLI GSAIPLTAYI LWQLVTLGAI
     SSNTFVGILA QQSGLNGLLQ AVREVVASPK VELAVHLFAD LALATSFLGV SLGLFDYLAD
     LLKRRNHAKE RLQTGLITFV PPMLCALFYP NFVMALTFAA VALSILALLL PSLLVWRCRQ
     ENQGGYRVKG GRPALVLIFL CGIAIIAIQI GIVTGILPEV G
//