ID A0A1N6NIV5_9BACI Unreviewed; 225 AA.
AC A0A1N6NIV5;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=SAMN05443094_101170 {ECO:0000313|EMBL:SIP91973.1};
OS Domibacillus enclensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Domibacillus.
OX NCBI_TaxID=1017273 {ECO:0000313|EMBL:SIP91973.1, ECO:0000313|Proteomes:UP000186385};
RN [1] {ECO:0000313|EMBL:SIP91973.1, ECO:0000313|Proteomes:UP000186385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIO-1016 {ECO:0000313|EMBL:SIP91973.1,
RC ECO:0000313|Proteomes:UP000186385};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
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DR EMBL; FTLX01000001; SIP91973.1; -; Genomic_DNA.
DR RefSeq; WP_045851069.1; NZ_MWSK01000001.1.
DR AlphaFoldDB; A0A1N6NIV5; -.
DR STRING; 1017273.SAMN05443094_101170; -.
DR OrthoDB; 9792284at2; -.
DR Proteomes; UP000186385; Unassembled WGS sequence.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:SIP91973.1};
KW Protease {ECO:0000313|EMBL:SIP91973.1};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 27..220
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 225 AA; 24639 MW; D972170406A7A22F CRC64;
MAKVIAVLSS GHKDEQNNYE TGWWAEELFA PLERLEGAGH TVDLASPLGG KPVLDQVSLQ
SDYDPDGKYK AMYESGRADS TVKLADVHAR EYDALLIVGG HGAMYDLAKD SHLHSLINDM
YDQGSIVAAE CHGPAPLIWA TRPDGKSIIE GKTVTGYPNE IEPEGLLDIL PFSLEDELTK
TARYDKGSLE KKAHAVWADD QIVTSRDPFS SELMGEELVK ALKNK
//
