ID A0A1N6QIV1_9ACTN Unreviewed; 432 AA.
AC A0A1N6QIV1;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Signal transduction histidine kinase {ECO:0000313|EMBL:SIQ16498.1};
GN ORFNames=SAMN05444858_101357 {ECO:0000313|EMBL:SIQ16498.1};
OS Micromonospora avicenniae.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1198245 {ECO:0000313|EMBL:SIQ16498.1, ECO:0000313|Proteomes:UP000186004};
RN [1] {ECO:0000313|EMBL:SIQ16498.1, ECO:0000313|Proteomes:UP000186004}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45758 {ECO:0000313|EMBL:SIQ16498.1,
RC ECO:0000313|Proteomes:UP000186004};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FTNF01000001; SIQ16498.1; -; Genomic_DNA.
DR RefSeq; WP_076466777.1; NZ_FTNF01000001.1.
DR AlphaFoldDB; A0A1N6QIV1; -.
DR STRING; 1198245.SAMN05444858_101357; -.
DR OrthoDB; 4198152at2; -.
DR Proteomes; UP000186004; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR025828; Put_sensor_dom.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF13796; Sensor; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SIQ16498.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186004};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..212
FT /note="Putative sensor"
FT /evidence="ECO:0000259|Pfam:PF13796"
FT DOMAIN 241..304
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT DOMAIN 348..432
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
SQ SEQUENCE 432 AA; 45831 MW; AE4EB036F1EAB44B CRC64;
MTTVTVAANQ SKLAPTVTRQ LLLDSGYVLL GLPLALASFV VLLAGTALGI GLMVTVIGLP
VLAGTLYAAR GLADIERLRL PSVLHQPRVR PHYRAAEPGA SAWRRIFVPI ADAQSWLDLA
HGIFKLIVTV STFVVTVVWW AGAVGGTLYW VYDWALPRSP DETDLAELLG LGSSTLSRVG
LYTAVGVFFL ITLPIVVRGC ALLQASFSRA MLTGVAEMRD RIIVLEEQKR AAASAEATAL
RRLERDIHDG PQQRLVRLAM DLSRARQQLA SDPEAAGRTL DEAVAQTRDT LAELRALSRG
IAPPILVDRG LPSALAALAG RGLIPIELRV DPELGTPTGR LDPALENTAY FVVAESLTNV
AKHSRATECQ VSVQRSGRRL TVSVGDDGQG GAHVAKGHGL AGIADRVRAA GGELVVVSPP
GGPTEVRADL PL
//
