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Database: UniProt
Entry: A0A1N6QY70_9SPIO
LinkDB: A0A1N6QY70_9SPIO
Original site: A0A1N6QY70_9SPIO 
ID   A0A1N6QY70_9SPIO        Unreviewed;       364 AA.
AC   A0A1N6QY70;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   08-MAY-2019, entry version 9.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=SAMN05920897_10597 {ECO:0000313|EMBL:SIQ21580.1};
OS   Alkalispirochaeta americana.
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae;
OC   Alkalispirochaeta.
OX   NCBI_TaxID=159291 {ECO:0000313|EMBL:SIQ21580.1, ECO:0000313|Proteomes:UP000186400};
RN   [1] {ECO:0000313|EMBL:SIQ21580.1, ECO:0000313|Proteomes:UP000186400}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ASpG1 {ECO:0000313|EMBL:SIQ21580.1,
RC   ECO:0000313|Proteomes:UP000186400};
RA   Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; FTMS01000005; SIQ21580.1; -; Genomic_DNA.
DR   RefSeq; WP_076488239.1; NZ_FTMS01000005.1.
DR   BioCyc; GCF_900156105:BW950_RS05235-MONOMER; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000186400; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000186400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186400};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       43    337       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   364 AA;  39595 MW;  415C3F2708EFCB19 CRC64;
     MPKISDIHVT AESPLLAPAE LKRRLPISDA CAETVLRSRR EITDILEGRD PRMVAVVGPC
     SIHDGRSAID YARKIRVLQE ELSDVLLLVM RVYFEKPRTA LGWRGLILDP NLDGSYDIDQ
     GLHTAREILL AVTAMGVPAG SEMLDPIVPQ YIDDLVSWAS IGARTIESQT HREMASGLSM
     PVGFKNGTDG SIETALNAMI SSLRPHSFIG IDQEGSTAVI HTTGNRAVHV ILRGGRGGPN
     YQSWDIVRVE ELLRSMDLPL NILVDCSHGN SEKDPRRQTK VLSSILDQRL GGRRSITGFM
     LESNLVAGRQ DLAGDPSRLV YGQSITDACI GWDETVGLLR EAAGRLRNDT GPGDALHTRG
     GGAK
//
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