ID A0A1N6QZK4_9ACTN Unreviewed; 349 AA.
AC A0A1N6QZK4;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Predicted naringenin-chalcone synthase {ECO:0000313|EMBL:SIQ21942.1};
GN ORFNames=SAMN05444858_101541 {ECO:0000313|EMBL:SIQ21942.1};
OS Micromonospora avicenniae.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1198245 {ECO:0000313|EMBL:SIQ21942.1, ECO:0000313|Proteomes:UP000186004};
RN [1] {ECO:0000313|EMBL:SIQ21942.1, ECO:0000313|Proteomes:UP000186004}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45758 {ECO:0000313|EMBL:SIQ21942.1,
RC ECO:0000313|Proteomes:UP000186004};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
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DR EMBL; FTNF01000001; SIQ21942.1; -; Genomic_DNA.
DR RefSeq; WP_076467384.1; NZ_FTNF01000001.1.
DR AlphaFoldDB; A0A1N6QZK4; -.
DR STRING; 1198245.SAMN05444858_101541; -.
DR OrthoDB; 9786288at2; -.
DR Proteomes; UP000186004; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000186004}.
FT DOMAIN 37..200
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 220..345
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 140
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 349 AA; 37024 MW; B2FD0BF4F48DC33C CRC64;
MSVPVIAGLG TAQPPSARQD ELWEGFFSRH FTGTTRSLAQ RIFANSGVTT RQAAVNPLLE
DVSDWPTERR MRRYLVEALP LGKEAVGRAL TAAGLDAGDI GLFVVCSCTG YATPGLDILL
ARDLGMAPGT QRMFVGHMGC YAALPGLGAA SDFVTARGRP ALLLCAELTS LHIQPSTARV
DTQQIVSHAL FSDAAVAAVV LPGGPGYALR EVTSVTDTST ADHMTWDVTD AGFRMGLSPK
VPQVLSTHVR GLVDDLLARH GATLDEVDGW AVHPGGPRIL NVVERELGLP PEALAASRAT
LDEHGNCSSP TVLLILDRLR RAPTPPERIL MLAFGPGLTL YAVLLDRQG
//
