ID A0A1N6URF5_9GAMM Unreviewed; 1060 AA.
AC A0A1N6URF5;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Efflux pump membrane transporter {ECO:0000256|RuleBase:RU364070};
GN ORFNames=SAMN05421647_107169 {ECO:0000313|EMBL:SIQ68051.1};
OS Marinobacterium stanieri.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinobacterium.
OX NCBI_TaxID=49186 {ECO:0000313|EMBL:SIQ68051.1, ECO:0000313|Proteomes:UP000186895};
RN [1] {ECO:0000313|EMBL:SIQ68051.1, ECO:0000313|Proteomes:UP000186895}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7027 {ECO:0000313|EMBL:SIQ68051.1,
RC ECO:0000313|Proteomes:UP000186895};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU364070}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU364070}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. {ECO:0000256|ARBA:ARBA00010942,
CC ECO:0000256|RuleBase:RU364070}.
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DR EMBL; FTMN01000007; SIQ68051.1; -; Genomic_DNA.
DR RefSeq; WP_076464032.1; NZ_FTMN01000007.1.
DR AlphaFoldDB; A0A1N6URF5; -.
DR STRING; 49186.SAMN05421647_107169; -.
DR eggNOG; COG0841; Bacteria.
DR Proteomes; UP000186895; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042908; P:xenobiotic transport; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004764; MdtF-like.
DR InterPro; IPR000731; SSD.
DR NCBIfam; TIGR00915; 2A0602; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF78; CATION OR DRUG EFFLUX SYSTEM PROTEIN; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU364070};
KW Cell membrane {ECO:0000256|RuleBase:RU364070};
KW Membrane {ECO:0000256|RuleBase:RU364070};
KW Reference proteome {ECO:0000313|Proteomes:UP000186895};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364070};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364070}; Transport {ECO:0000256|RuleBase:RU364070}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 343..362
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 369..389
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 395..416
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 442..462
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 474..501
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 546..564
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 878..896
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 903..923
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 935..955
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 976..997
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 1009..1035
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT DOMAIN 369..499
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 1060 AA; 113965 MW; 33272B695208297A CRC64;
MNFANFFIKR PIFATVLAII LTVIGVVSLR VLPIEQYPSV VPPSVSVEAT FPGANAETVA
QTVAAPLAEA INGVEDMIYM TSTSADNGLM SMEVSFNVGT DGDMNTVNVN NRVQGALSQL
PDSVRAQGVK VEQRSNSILL LLALISPEGD YDNVYMQNYA TLNILDELRQ IPGVGAAEVL
GGGEFAMRVW MDPQKLAQYD LTPTEVAAAI RAQNTEVPAG NLAGTPQSEP RAYTYTVNAG
GRLSSADDFR NIYLRTNADG SALLLKDVAR VELGASFYGV EARLDSATMA PIIINQQPGA
NALETADAVK AKVEELSQRF PPGLEYVVPY DTTLFISASV DTVIQTFIEA FLIVGVILYV
FLQNWRFTII AMSVVPVSVV ATFAGFYLFD FSLNLLTLFA LVLSIGIVVD DAILVVENVE
RVLAEDENIS VREATVLAMK EVGGPVIATS FIMAAVFIPV AFLGGFTGQI YQQFALTVAI
SVGFSALMAL TFTPALSAVF IKHHKPGEKE SGFMHAFHAP LRWFERGFSA VTALFTRIVT
FLVRRWVVAL VLTAGFSYAS WWMFANTPTT LVPQTDQGIV LVSVQLPDAA SLDRTNDYMD
NVSKQIQEIP GVDHVAAVAG YDILTSAVNS ARGVMFVSLV PWEDRDLKVD PLIGQIMQIG
AMTPGGSAIA FNMPPIMGLS TTGGFTGYLQ SYGGASPEEL YQASVKVMQA ANEHPALNRV
FTTFNVNVPS YRAEIDRQKA LSYGVALEDL NATLSNTLGN GFVNYFSYQN RNFQVFLQNE
DAYRQQPDDL NTIFVRSGIS GERLPLSELV TLERQLAPAV VSRFGVYLGA QFQGGPATGY
SSGQAVAAME EVVQETLGDN WGMGWTGTAY QETTVGNTAA LAVGFGILMM FLILAAQYES
WSLPLAVLTA TPFAFFGAVG GIMMRSLDVS VYVEIGLLVV VGLAAKNAIL IVEFAELQRR
ELGKSIQEAA ITAAELRFRP IVMTSLAFIL GTIPLALATG ASDTSSHHIG TAVSVGMASV
AIIGSCFVPT FYAMIASVSE WLQSKRSSSD EQGKVGDVTS
//
