ID A0A1N6WGV1_9ACTN Unreviewed; 445 AA.
AC A0A1N6WGV1;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Metabolite-proton symporter {ECO:0000313|EMBL:SIQ89230.1};
GN ORFNames=SAMN05421833_104196 {ECO:0000313|EMBL:SIQ89230.1};
OS Microbispora rosea.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Microbispora.
OX NCBI_TaxID=58117 {ECO:0000313|EMBL:SIQ89230.1, ECO:0000313|Proteomes:UP000186096};
RN [1] {ECO:0000313|EMBL:SIQ89230.1, ECO:0000313|Proteomes:UP000186096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12950 {ECO:0000313|EMBL:SIQ89230.1,
RC ECO:0000313|Proteomes:UP000186096};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FTNI01000004; SIQ89230.1; -; Genomic_DNA.
DR RefSeq; WP_076433959.1; NZ_FTNI01000004.1.
DR AlphaFoldDB; A0A1N6WGV1; -.
DR STRING; 58117.SAMN05421833_104196; -.
DR OrthoDB; 3768022at2; -.
DR Proteomes; UP000186096; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17369; MFS_ShiA_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR43045; SHIKIMATE TRANSPORTER; 1.
DR PANTHER; PTHR43045:SF1; SHIKIMATE TRANSPORTER; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 12..422
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 445 AA; 46989 MW; 249E0D0CD9A77DC6 CRC64;
MANTPPARIG KVVGASLIGT TIEWYDFFLY GSAAALVFNK LFFPTEDELT GTLLAFLTYA
VGFVARPLGG LVFGHYGDRL GRKRLLVISL LMMGGSTFLI GCLPTYAALG AGAPLLLTLL
RLVQGFALGG EWGGAVLLVS EHGDPRNRGF WASWPQAGAP GGNLIATGVL ALLAAVQSEE
AFLAWGWRIA FLLSGVLVLI GLWIRLTVTE SPVFQQALER QEPAPQAPII GVLRHHWRDV
LVAMGARMAE NVSYYVITAF VLVYGTTTAG LPKGTVLNAV LIGSAIHFVT IPLWGALSDR
IGRRPVYLLG AAAVGLWAFA FFPLIDTKNF ALVTVAVTVG LVLHGAMYGP QAAFFSELFA
TRMRYSGVSI GYQLASIAAG GVAPLIAVAL LDAYGSSVPI SVYVVAAAIL TIIAVIASRE
TRDRDLSAIE PTSGAAQTAV IAKEA
//
