ID   A0A1N6WRV0_9SPIO        Unreviewed;      1476 AA.
AC   A0A1N6WRV0;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=CoA-substrate-specific enzyme activase, putative {ECO:0000313|EMBL:SIQ92775.1};
GN   ORFNames=SAMN05920897_11859 {ECO:0000313|EMBL:SIQ92775.1};
OS   Alkalispirochaeta americana.
OC   Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Spirochaetaceae;
OC   Alkalispirochaeta.
OX   NCBI_TaxID=159291 {ECO:0000313|EMBL:SIQ92775.1, ECO:0000313|Proteomes:UP000186400};
RN   [1] {ECO:0000313|EMBL:SIQ92775.1, ECO:0000313|Proteomes:UP000186400}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ASpG1 {ECO:0000313|EMBL:SIQ92775.1,
RC   ECO:0000313|Proteomes:UP000186400};
RA   Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR   EMBL; FTMS01000018; SIQ92775.1; -; Genomic_DNA.
DR   STRING; 159291.SAMN05920897_11859; -.
DR   OrthoDB; 9802715at2; -.
DR   Proteomes; UP000186400; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.40; -; 4.
DR   InterPro; IPR002731; ATPase_BadF.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018709; CoA_activase_DUF2229.
DR   InterPro; IPR008275; CoA_E_activase_dom.
DR   NCBIfam; TIGR00241; CoA_E_activ; 1.
DR   PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR   PANTHER; PTHR32329:SF2; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR   Pfam; PF01869; BcrAD_BadFG; 2.
DR   Pfam; PF09989; DUF2229; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186400}.
FT   DOMAIN          72..250
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          302..562
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          674..886
FT                   /note="DUF2229"
FT                   /evidence="ECO:0000259|Pfam:PF09989"
FT   REGION          1429..1476
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1476 AA;  161984 MW;  78F13657354C7B21 CRC64;
     MNTLGISLGS SSIKLVHMKN HSIEWWRVIP HEGAVISVLE RELALQKLPR GTRVLVTGTE
     ARELVQAASA IEPLCLERAL AKREQGAEPA VAIVSMGGEE LILYTLDEQG HVRGNFSGNK
     CASGTGEFFR QQLGRMHMEL DEVNLIPEDT ATCALSSRCS VFMKSDCTHK LNKRQASREE
     ITVSLSQVMA TKVADFLSRA KISSGRVILT GGITANRHVL RALRGLAPEI TFDVPPEAVF
     YEAFGAALLA EEAGTIPDDT SQMVQEARIR FERFPSLRTA QNRVTYFEEI REPLQAGGRY
     ILGIDGGSTT TKVCLVNTET GRIAASHYGR THGDPVRALK VCLSELQKQI QDQLGDGATL
     VVELAATTGS SRETLGLFVE TPGVYNEIIA HACGTTQFSD QVDTIFEIGG QDAKYVLLQN
     RVPIDYAMNE ACSAGTGSFL EESAAGDLNI PYAHQIGDLA LQAAAPLKFG EHCSAFINSD
     IRKAIAQGAS REDITAGIVT SVVANYLNRV VGNRTIGKTV FLQGGVAKNE AVAPAFAMLL
     NRDILVPPDP ELMGCYGVAI LAREKNRQGL LEKGNWALER ILATEIFEKG EFVCSSCDNL
     CPIRILEVNG HRRFFGGRCS KYSNSGARAS SVGASGTTTA PGEAVNYVDE RNRLLFQEYA
     APAAPAESPS ATLTVGIPRS FSVHSLYPFY SWFFHTLGFR TVLSDGVDRK GVARVESSYC
     FPAEIAHGAV QNVIDKGVDF IFTPHVRDLE SYEDSVHANF CPITQGLPYY IRKAFPDIPP
     ERFLDVVVSF KHGPGKARDF FRKLALPLGV SEARIDAAFA LALEKQQAYR EAAQALGQQA
     LAEARENQRS VIALLGRPYN AFTSEANMGI PRKFTSRGHV VIPFDILPLE EGQEIFPNMY
     WYYGQQDMKA SALLKDEPNI YVTFISNFSC APDSFLLHYL KWQMGTKPFL ILELDSHSAD
     AGIDTRIEAF LDIVEGYASR RDSLAEERYD NGLRLVVPEN GDIVVHNSNT GEDIPVRDNP
     SVQLLLSNMG ELGTELLAAV IRSRGINAQA LPPADSHTVM IARGHCSGKE CVPAHLVLGN
     VLQFLASDQY RKDEIYLVFV PITTGPCRTG QYYVFYENLF RDLRIDNLVI FTMSADNSYT
     EIGPDVGAAM WQSLVISDYM KDIETALRTC AEDPGEAITL YRQEWQKLVQ RAEGNFSDIY
     PALKEAAQVF QAIPLARDLS QVPKALVVGE IYVRRDDYAV DELVGTLARQ GIMAKVSGVS
     EWIHYLDFVR DYELRKRLSL RPLWVRPFAQ EARALLRLGL ERAWKHRIEQ RVLKILATAR
     LVPPGPGTMK KIMERTKTHF VNPELNSEIA VSTGAAAAAM ENGYSGIVNI SPFACLIGRV
     IEGVFAPWAR TRNYPLLSVE VDGNQLPPTT LNRLNVFAVN VSRYNGHDNG EGFPHGTGLP
     LEGVSPSGRG SDPCVEAAGS CTGGPLRPGQ VLPRES
//