ID A0A1N6X875_9EURY Unreviewed; 436 AA.
AC A0A1N6X875;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Carboxypeptidase Q {ECO:0000256|ARBA:ARBA00014116};
DE AltName: Full=Plasma glutamate carboxypeptidase {ECO:0000256|ARBA:ARBA00033328};
GN ORFNames=SAMN05421858_1031 {ECO:0000313|EMBL:SIQ98558.1};
OS Haladaptatus litoreus.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haladaptataceae; Haladaptatus.
OX NCBI_TaxID=553468 {ECO:0000313|EMBL:SIQ98558.1, ECO:0000313|Proteomes:UP000186914};
RN [1] {ECO:0000313|Proteomes:UP000186914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.7737 {ECO:0000313|Proteomes:UP000186914};
RA Varghese N., Submissions S.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. The monomeric form is inactive while the homodimer
CC is active. {ECO:0000256|ARBA:ARBA00025833}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC {ECO:0000256|ARBA:ARBA00004240}. Golgi apparatus
CC {ECO:0000256|ARBA:ARBA00004555}. Lysosome
CC {ECO:0000256|ARBA:ARBA00004371}.
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DR EMBL; FTNO01000001; SIQ98558.1; -; Genomic_DNA.
DR RefSeq; WP_076428545.1; NZ_FTNO01000001.1.
DR AlphaFoldDB; A0A1N6X875; -.
DR OrthoDB; 18376at2157; -.
DR Proteomes; UP000186914; Unassembled WGS sequence.
DR GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0070573; F:metallodipeptidase activity; IEA:InterPro.
DR CDD; cd04819; PA_2; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR039866; CPQ.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR PANTHER; PTHR12053:SF3; CARBOXYPEPTIDASE Q; 1.
DR PANTHER; PTHR12053; PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 4: Predicted;
KW Carboxypeptidase {ECO:0000256|ARBA:ARBA00022645,
KW ECO:0000313|EMBL:SIQ98558.1};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022645, ECO:0000313|EMBL:SIQ98558.1};
KW Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW Protease {ECO:0000256|ARBA:ARBA00022645, ECO:0000313|EMBL:SIQ98558.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186914}.
FT DOMAIN 95..185
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 209..387
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
SQ SEQUENCE 436 AA; 47322 MW; 98AD78222706201F CRC64;
MSQWIGRTFT SDAGWDFLET IVDVGDRMAG SDGERRGAEA ARDALESVGA RNARLDEYDI
QGWERGTSAI HAGDTAQDAI ALPRSPSGGA DGEFVNLGYG LPADFEENDI EGKVVMVASN
VPSYYDRFIH RREKYYYAVE GGAAAFVFRN HVEGCLPPTG SVGTEADPIG DIPAVGVSKE
VGSRLARRWE GDDVTVEVEA NIHDATSQNV HAELGPDTDE QILVSSHIDG HDIAEGAMDN
GAGSAMVVEL ARALAEREDE LETKVHFVAF GSEEVGLVGS GHMAEETDHD SIKAIVNNDG
VARGRTLSFY THGFDELRDA ANEIADEFGH PITTIPQQGP HSDHWPFVQW GVPGYHVMSE
TGDEGRGWGH TFADTLDKVE VRDLREQAIL LTELTVHLAS DEFEVSNKDP EEIADALEAE
DQAAGMKIIG DWPYDE
//
