ID A0A1N6XRG5_9EURY Unreviewed; 489 AA.
AC A0A1N6XRG5;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Multidrug-efflux transporter {ECO:0000256|ARBA:ARBA00031636};
GN ORFNames=SAMN05421858_1243 {ECO:0000313|EMBL:SIR04903.1};
OS Haladaptatus litoreus.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haladaptataceae; Haladaptatus.
OX NCBI_TaxID=553468 {ECO:0000313|EMBL:SIR04903.1, ECO:0000313|Proteomes:UP000186914};
RN [1] {ECO:0000313|Proteomes:UP000186914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.7737 {ECO:0000313|Proteomes:UP000186914};
RA Varghese N., Submissions S.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FTNO01000001; SIR04903.1; -; Genomic_DNA.
DR RefSeq; WP_076428903.1; NZ_FTNO01000001.1.
DR AlphaFoldDB; A0A1N6XRG5; -.
DR OrthoDB; 214119at2157; -.
DR Proteomes; UP000186914; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR CDD; cd13142; MATE_like_12; 1.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR048279; MdtK-like.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR43298:SF2; FMN_FAD EXPORTER YEEO-RELATED; 1.
DR PANTHER; PTHR43298; MULTIDRUG RESISTANCE PROTEIN NORM-RELATED; 1.
DR Pfam; PF01554; MatE; 2.
DR PIRSF; PIRSF006603; DinF; 1.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186914};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 418..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 489 AA; 51864 MW; C5AF817CEC79DDCA CRC64;
MSSKNLDVNL TDGELLKPLL VLSFPIVLSQ LMQVAYNLAD TFWVGRLGQD AVSALSFSWP
LVFLMISVGG GFTVAGTVLV AQNKGAGNHD RVDHIAGQTI AFVTAIAVAF SILGWFLTPT
LLSLIGTTPG TQVHAYSVEY TRTIFLGVFF MFGFFIFQAL LRGWGDTKTP MYLMAFGVVI
NVVLDPFFIL GFQDNPLFGY IGMRGLEATL FDATGFTGFG VQGAAFATVL SRGVGAVVGF
ALLFSGRVGI HLSLDDLRLR AESVKKIVQI GGPTSVEQST RALGITAMTA LVALAGTDAV
AAFGIGNRLT SLVFLPALGL AQGTETVVGQ NLGAEKIERA KRAVYLATGI IMAVLAVVGT
VAYIFAEPIT SIFITGEGSA NVIEIGGEYL RIVGPTFIGI GVFRIISGGF RGSGSTRVAM
VLSILSLWVF RLPPAYALVE WYDMGSTGIW YGIALSNVLT AIVAAAWFLR GTWTDSVVES
SKKPTVADD
//
